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Scientists study brain functions and chemistry using advanced techniques like MRI and PET scans. Understanding neurotransmitters helps explain diseases like schizophrenia and addiction caused by drug-induced changes.
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KEY CONCEPT Scientists study the functions and chemistry of the brain.
New techniques improve our understanding of the brain. • Today, scientists study the brain without surgery.
CT (computerized tomography)uses x-rays to view structure. • There are three common technologies. • MRI (magnetic resonance imaging) uses magnetic fields and radio waves to view structure. • PET detects activity, uses radioactive glucose
synapse receptor neurotransmitter What alters brain chemistry? Drugs and Illness • Different neurotransmitters relate to different functions. Normal • some stimulate impulses • some prevent impulses
Schizophrenia, Parkinson’s, Alzheimer's disease • depression • Abnormal levels of neurotransmitter can cause illness. Schizophrenic Normal Depressed
Drugs alter brain chemistry. • Addiction is the physiological need for a substance. • Tolerance occurs when more drug is needed to produce an effect. • Drugs might cause desensitization or sensitization. • desensitization: more neurotransmitter leads to fewer receptors • sensitization: less neurotransmitter leads to more receptors. When the amount of neurotransmitter becomes abnormal, the adjacent neuron adapts.
cocaine neurotransmitter synapse • may increase neurotransmitter in synapse • may decrease removal of neurotransmitter in synapse • Stimulants cause more action potentials
may produce neurotransmitter that prevent impulses • may slow release of neurotransmitter that generates impulses • Depressants cause fewer action potentials.
Open books to page 891Define the termsAnswer this questions alsoMake a list of the five neurotransmitters on page 892 and describe each function.