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IDENTIFYING THE MELANOMA WAVELENGTHS. E. De Fabo, EOH, SPHHS, GWUMC drmecd@gwumc.edu 202-994-3975. 6/18 (1.0). BLACK. 20/24 (3.7). ALBINO. Effect of pigment on melanoma. E. De Fabo, EOH, SPHHS, GWUMC. FVB HGF/SF. FVB HGF/SF. C57BL6 HGF/SF. C57BL6 HGF/SF. UVB. UVA. STRAIN 1.
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IDENTIFYING THE MELANOMA WAVELENGTHS E. De Fabo, EOH, SPHHS, GWUMC drmecd@gwumc.edu 202-994-3975
6/18 (1.0) BLACK 20/24 (3.7) ALBINO Effect of pigment on melanoma E. De Fabo, EOH, SPHHS, GWUMC
FVB HGF/SF FVB HGF/SF C57BL6 HGF/SF C57BL6 HGF/SF UVB UVA STRAIN 1 STRAIN 2 De Fabo et al., Cancer Res., 2004; in prep. E. De Fabo, EOH, SPHHS, GWUMC
GFP Induction 24 Hrs Post-DoxR.Zaidi, NCI,NIH • Pups were injected doxycycline on the day of birth. • Back skins were harvested 24 hours after the doxycycline injection and imaged for GFP. Dct-rtTA–/ GFP+ Dct-rtTA+ / GFP+ E. De Fabo, EOH, SPHHS, GWUMC
UVB + PIGMENT STRAIN-2 UVA + PIGMENT STRAIN-2 UVB + ALBINO STRAIN-1 UVA + ALBINO STRAIN-1 E. De Fabo, EOH, SPHHS, GWUMC
ACKNOWLEDGEMENTS • THE GEORGE WASHINGTON UNIVERSITY • SCHOOL OF PUBLIC HEALTH & HEALTH SERVICES • FRANCES NOONAN • JESSE BAHN • SCHOOL OF MEDICINE & HEALTH SCIENCES • TERESA HAWLEY • ALI RAMEZANI • NIH/NCI • RAZA ZAIDI: Laboratory of Cancer Biology & Genetics • GLENN MERLINO: Chief, Laboratory of Cancer Biology & Genetics • PAUL MELTZER: Chief, Cancer Genetics Branch • Funding- NCI/NIH; Elaine Snyder Cancer Research Fund, GWUMC E. De Fabo, EOH, SPHHS, GWUMC