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The Impact of Vitamins and Supplements

The Impact of Vitamins and Supplements. March 13, 2013. Presented by Georgia Tetlow, MD. The Impact of Vitamins and Supplements. The Impact of Vitamins and Supplements. Disclosure/Disclaimer. Disclaimer

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The Impact of Vitamins and Supplements

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  1. The Impact of Vitamins and Supplements March 13, 2013 Presented by Georgia Tetlow, MD

  2. The Impact of Vitamins and Supplements Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  3. The Impact of Vitamins and Supplements Disclosure/Disclaimer Disclaimer • Information is intended for educational purposes only, not as medical or psychological adviceor treatment Nothing that isn’t disclosed • I have an online store that benefits educational programs • Monthly educational webinars Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  4. The Impact of Vitamins and Supplements • Integrative Medicine • Key research pearls • Vitamin D • Omega 3’s • Dairy • Soy • Lifestyle choices • Smoking • Weight • Alcohol • Green tea • Emotional/spiritual health, social connection, mindfulness Agenda Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  5. The Impact of Vitamins and Supplements Integrative Medicine • Combines best of conventional medicine • Cancer fighting drugs, therapies, surgery • With additional safe, effective approaches, treatments • Evidence-based = standard for medicine • JUST GOOD MEDICINE • Need provider who is open to all the evidence and who is trained Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  6. The Impact of Vitamins and Supplements Integrative Medicine continued… • Biological interventions • Vitamins and Supplements • Whole Food diet • Mind-Body Medicine • Alternative Medical Systems • Traditional Chinese Medicine, Ayurveda, Homeopathy • Energy Medicine • Acupuncture • Hands-On medicine Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  7. The Impact of Vitamins and Supplements Integrative Medicine “Integrative medicine honors the innate ability of the body to heal, values the relationship between patient and physician, and integrates complementary and alternative medicine to support the organism and facilitate healing.” ---Victoria Maizes, MD, Executive Director University of Arizona Center for Integrative Medicine Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  8. The Impact of Vitamins and Supplements Why Integrative Medicine? • Patient at the center • Addresses the full range of physical, emotional, mental, social, spiritual and environmental influences • Personalized strategy that considers the patient’s unique conditions, needs and circumstances • Health as “a state of complete physical, mental and social wellbeing and not merely the absence of disease or infirmity.”* *Constitution of the World Health Organization — Basic Documents, Forty-fifth edition, Supplement, October 2006. Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  9. The Impact of Vitamins and Supplements About Georgia Tetlow, MD • Graduate Fellow, University of Arizona Center for Integrative Medicine • CEO, Founder of Philadelphia Integrative Medicine • Clinical Assistant Professor of Rehabilitation Medicine Thomas Jefferson Medical College • Yoga Teacher for 20 years • Mindfulness teacher Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  10. The Impact of Vitamins and Supplements Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  11. The Impact of Vitamins and Supplements Your Plate Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  12. The Impact of Vitamins and Supplements Your Plate • No one food ingredient • Eat from the rainbow • Broccoli/cabbage family • Indole-3-carbinol • Supports immune system, reduces cellular damage balances hormones • Collards, mustard greens, turnips, cabbage, broccoli, kale, cabbage, cauliflower and Brussels sprouts • Food choices for healthy weight • 5 or more servings of vegetables and fruit daily Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  13. The Impact of Vitamins and Supplements Antioxidants • Reduce inflammatory and toxic cell mediators • NFkB, Il-6, Il-8 • Donate electrons to electron-deficient free radicals • Neutralize them! • Cells and DNA protected, help prevent cancer Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  14. The Impact of Vitamins and Supplements Why Supplements, Anyway? • Strengthen the immune system • Reduce inflammation • Reduce free radicals • Reduce DNA damage that leads to cancer Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  15. The Impact of Vitamins and Supplements Pearl 1 • Whole foods and healthy diets should be the primary approach in designing studies to test nutrition-cancer associations • Experts believe components in many foods, especially fruits and vegetables, act synergistically to reduce cancer risk Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  16. The Impact of Vitamins and Supplements Pearl 2 • Seek products that most closely mimic the forms that nutrients naturally take in food, such as vitamin E in the form of mixed tocopherols and tocotrienols or vitamin A in the form of mixed carotenoids (vs. β-carotene alone or vitamin A palmitate) • Dosage, duration and quality matter Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  17. The Impact of Vitamins and Supplements Pearl 3 • The greatest benefit from taking supplements of any kind seems to be for those who are deficient in a particular nutrient "Diet, anthropometric measures and prostate cancer risk: a review of prospective cohort and intervention studies." Dagnelie PC, et al. BJU international 93(8):1139-50 May, 2004 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  18. The Impact of Vitamins and Supplements Pearl 4 • Genetic differences contribute to individual variation in response to foods and nutrients • Genetics influence the rates of absorption, metabolism and sites of action of individual constituents • Unmeasured, uncharacterized gene variation likely explains inconsistent findings across studies and across different populations Milner, JA. "Incorporating basic nutrition science into health interventions for cancer prevention.” The Journal of nutrition 133(11 Suppl 1):3820S-3826S Nov, 2003 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  19. The Impact of Vitamins and Supplements Vitamin D3 (Cholecalciferol) • Hormone • Controls phosphorus, calcium and bone metabolism and neuromuscular function • The only vitamin the body can manufacture from sunlight • More and more people deficient due to indoor living, heliophobia and sunscreen use Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  20. The Impact of Vitamins and Supplements Vitamin D3 (Cholecalciferol) continued… • Approx. 1 billion* may be Vitamin D3 deficient • Dark skin, obesity, heredity may hinder production • Elderly may need more D3 (decreased skin, renal synthesis) • Test: 25 (OH) Vitamin D • <30 ng/mL insufficient • 45 ng/mL adequate • 60-80 ng/mL more optimal *world wide Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  21. The Impact of Vitamins and Supplements Vitamin D3 continued… Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  22. The Impact of Vitamins and Supplements Fats, Omega 3’s • Cook with Olive Oil • FISH OIL (Omega 3’s fatty acids) • modulate estrogen metabolism, estrogen receptors • Must be triglyceride • 1-3 grams daily, with food, discuss with doctor • mercury/toxin free • many benefits • thins the blood Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  23. The Impact of Vitamins and Supplements Fish Oil Slows Tumor Growth Hardman, J. Nutr. 132:3508S-3512S, 2002 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  24. The Impact of Vitamins and Supplements Dairy • Over 36 case-control plus 10 prospective cohort studies showed inconsistent findings • Recent pooled analysis of American and European cohort studies found no association with dairy and postmenopausal breast cancer Moorman PG, et al. "Consumption of dairy products and the risk of breast cancer: a review of the literature." Moorman PG, et al. The American journal of clinical nutrition 80(1):5-14 Jul, 2004 MissmerSA, et al. "Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies." International journal of epidemiology 31(1):78-85 Feb, 2002 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  25. The Impact of Vitamins and Supplements Dairy continued… • Dietary calcium and low-fat dairy products associated with a moderately lower risk of postmenopausal breast cancer compared with women with lowest intake levels • Supplementalcalcium or higher levels of total calcium (diet plus supplements) were not related to overall breast cancer risk Moorman PG, et al. "Consumption of dairy products and the risk of breast cancer: a review of the literature." Moorman PG, et al. The American journal of clinical nutrition 80(1):5-14 Jul, 2004 MissmerSA, et al. "Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies." International journal of epidemiology 31(1):78-85 Feb, 2002 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  26. The Impact of Vitamins and Supplements Soy • Soy beans and fermented soy bean products such as tofu, tempeh and soymilk • Case-control studies support a protective effect of soy in the breast • case-control study among Korean women stratified by menopausal and hormone receptor status of the tumors • significant 64% reduction in breast cancer risk (95% CI 0.20, 0.64) with higher soy consumption Cho YA, et al. "Effect of dietary soy intake on breast cancer risk according to menopause and hormone receptor status." European journal of clinical nutrition 64(9):924-32 Sep, 2010 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  27. The Impact of Vitamins and Supplements Soy continued… • This association may not only result from higher intake of soy but alsoin utero and early exposure and pre-pubertal and adolescent exposure during mammary gland development • In addition, soy intake among Asian women is strongly correlated with increased consumption of fruit and vegetables Butler LM, et al. "A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women." The American journal of clinical nutrition 91(4):1013-9 Apr, 2010 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  28. The Impact of Vitamins and Supplements Soy Conclusions • Moderate amounts in diet are safe and likely protective • Half serving a day servings per day • May not be advisable in advanced stage breast cancer as early evidence from cell culture studies suggest possible proliferative effect in the setting of metastatic carcinoma Messina M, et al. Can clinicians now assure their breast cancer patients that soy foods are safe? Women's health (London, England) 6(3):335-8 May, 2010 Martínez-Montemayor, et al. "Individual and combined soy isoflavones exert differential effects on metastatic cancer progression." Clinical & experimental metastasis 27(7):465-80 Oct, 2010 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  29. The Impact of Vitamins and Supplements Cancer: Factors Within Your Control • Smoking • Weight control/Exercise • Diet • Alcohol • (Fruits/vegetables, best fats, certain cancers: hormones in beef and milk) • Green tea • Omega 3 Fatty Acids • Vitamin D—get tested! • Healthy immune system—emotional and spiritual health, social connection Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  30. The Impact of Vitamins and Supplements Breast cancer prevention: 1drink daily or less Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  31. The Impact of Vitamins and Supplements Mind-Body Interventions -Mindfulness Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  32. The Impact of Vitamins and Supplements Mindfulness Literature • Witek-Janusek, et al (2008). Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, and Immunity, 22(6), 969-981. • Carlson, et al (2007). One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior, and Immunity, 21(8), 1038-1049. Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  33. The Impact of Vitamins and Supplements “Integrative medicine addresses the root causes of illness and suffering. These root causes involve many aspects of a person’s life, including the physical, but also the psychosocial, emotional, and spiritual dimensions as well.” --Dean Ornish, MD Founder and Director of the Preventive Medicine Research Center Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  34. The Impact of Vitamins and Supplements Return to Art of Medicine • Mind, Body and Spirit • Fight cancer, but focus is on health and returning to health • Power of life style choices! • Understand root causes Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  35. The Impact of Vitamins and Supplements Mission Philadelphia Integrative Medicine offers a comprehensive approach to health and healing which recognizes the whole person, and champions self-care for health, illness recovery and prevention through education, inspiration and empowerment. Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  36. 4wholeness.com An online community and resource for women with breast cancer who want information about how to integrate natural and holistic therapies with allopathic cancer treatment. If the HPERLINK above doesn’t work, copy and paste this link into your Internet browser: http://vimeo.com/28516754

  37. The Impact of Vitamins and Supplements Upcoming Webinar Detoxify Mind & Body – Today! • Friday, April 5, 2013 (12-1pm) • Detoxify your mind • Focus on your purpose • Address emotional blocks that undermine energy and reduce hope • Detoxify your body • Learn how the elimination diet profoundly detoxifies and potentially addresses hardest-to-treat symptoms • Webinars: less than $20 Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

  38. Thank you! www.philly-im.com 888-702-7974info@philly-im.com Georgia Tetlow, MD - Philadelphia Integrative Medicine – www.philly-im.com - 888-702-7974

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