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Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA. Goals. Diagnosed Diabetes, 1958-2010. Despite Increasing Prevalence, T2D Remains Undertreated. Limitations of Conventional Glucose-Lowering Agents. Limitations of Conventional Glucose-Lowering Agents (cont).

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Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

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  1. Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

  2. Goals

  3. Diagnosed Diabetes, 1958-2010

  4. Despite Increasing Prevalence, T2D Remains Undertreated

  5. Limitations of Conventional Glucose-Lowering Agents

  6. Limitations of Conventional Glucose-Lowering Agents (cont)

  7. The Need for Novel Antihyperglycemic Agents

  8. Pathophysiologic Pathways Affecting Glycemic Control in T2D

  9. SGLT2 and Glucose Control

  10. SGLT2: Novel Target for Glucose Control

  11. Currently FDA-approved SGLT2 Inhibitors

  12. Glycosuria: Concerns in Urgent Care Settings

  13. Clinical Trial Findings for SGLT2 Inhibitors

  14. Clinical Trial Findings for SGLT2 Inhibitors: Extraglycemic Effects

  15. SGLT2 Inhibitors: Risk of Hypotension

  16. Treating Patients With Type 2 Diabetes and CKD

  17. Abbreviations

  18. Abbreviations (cont)

  19. References

  20. References (cont)

  21. References (cont)

  22. References (cont)

  23. References (cont)

  24. References (cont)

  25. References (cont)

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