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Learn about the different types of diseases, including infectious and noninfectious, and how they affect the body. Explore genetic diseases, trends in infectious diseases, and the chain of infection. Discover how diseases are transmitted and how they can be treated.
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Diseases • Processes that affect proper body functioning accompanied by associated signs and symptoms • Noninfectious diseases - caused by genetic abnormalities, environmental factors, or a combination of both • Cystic fibrosis, lead-poisoning, asthma • Infectious diseases - caused by pathogens such as bacteria, viruses, fungi, parasitic worms • Colds, flu, sexually transmitted infections
Genetic Diseases • Two types: Inherited diseases (inherit “defective” gene) and diseases caused by errors when gametes are formed • Defective (mutated) genes caused by ionizing radiation, toxic chemicals, drugs • Common inherited diseases in the U.S. • Sickle-cell anemia • Cystic fibrosis • Duchenne muscular dystrophy
Noninfectious Diseases Caused by an Interaction of Genes and Environment • Asthma • Narrowed airway passages and difficulty breathing • Attacks can be triggered by air pollution, URIs, smoke, dust • Ulcers • Diabetes mellitus • Migraine headaches • Cardiovascular disease • Cancer
Trends in Infectious Disease • Infectious diseases are not significant contributors to death in the U.S. today • Worldwide, infectious diseases are the leading cause of death • Many strains of bacteria have become resistant to antibiotics • With international travel commonplace, transmission of infection is a worldwide concern
Chain of Infection • Agent of Infection (Pathogen) • Transmission • Host
Pathogens • Bacteria (unicellular organisms with a simple cell structure) • Cause diseases such as strep throat, pneumonia, food infection • Rickettsias (bacterialike organisms that live within host cells) • Cause diseases such as typhus, Rocky Mountain Spotted Fever
Pathogens (cont’d) • Viruses (hereditary material with a protein coat) • Cause diseases such as cold, flu, mumps, measles, chicken pox, hepatitis, HIV infection • Fungi (cause opportunistic infections) • Cause diseases such as athlete’s foot, yeast infections
Pathogens (cont’d) • Protozoans (single-celled organisms with a complex cell structure) • Cause disease such as malaria, “trich” infections • Parasitic worms • Tapeworms, roundworms, flukes • Live in digestive system and cause digestive disorders. Flukes can also inhabit the liver, lungs, or veins.
Pathogens (cont’d) • Arthropods • Lice, fleas, mites, and ticks • Cause infestations of various body parts
Transmission of Disease Noncommunicable Communicable
Noncommunicable Diseases • Caused by: Growth of bacteria that normally inhabit the body • Skin infections • Ingestion of toxins or poisons produced by some bacteria • Food poisoning or food infection • Pathogens that infect people via environment or animal sources
Communicable Diseases • Transmitted from person to person by • direct or indirect contact • a common vehicle (food, water, a common drinking glass) • the air • vectors (organisms other than humans, such as mosquitoes)
Host • Stress can reduce resistance to infection • Exhaustive exercise can lower immune system function • Race and age affect resistance or susceptibility to disease
Treating Infections • Antibiotics (kill or inhibit growth of bacteria) • Over-the-counter medications can sometimes relieve symptoms • Specific medications have been developed to treat certain viral and protozoan infections, and worm infestations
Sexually Transmitted Infections • Spread from person-to-person by intimate contact • Caused by certain viruses, bacteria, yeasts, and protozoans • Infestations caused by certain mites and lice
HIV Transmission • Sexual contact with infected person • Semen, vaginal secretions, or blood • Tears in skin and mucous membranes • Exposure to infected blood or blood products • Shared needles • Blood transfusions • Placental transfer during fetal development, labor/delivery, and breastfeeding
Yeast Infections • Candidiasis • Acquired through intercourse or develops in women after taking antibiotics • Itching, burning, irritation, swelling, and white vaginal discharge • Can be treated with OTC antifungal creams • Males may experience irritation, swelling, and a rash or white patches
SUMMARY • Noninfectious diseases have hereditary or environmental causes, or a combination of both • Genetic diseases are inherited • Two primary causes of infectious diseases are bacteria and viruses • The human body combats infectious disease with both specific and nonspecific types of immunity
SUMMARY (cont’d) • The severity of a disease depends on: • the type of organism • its virulence • how it spreads in the body • the chemicals it produces • its ability to combat the defense mechanisms of the body • the body’s reaction to the pathogen
SUMMARY(cont’d) • Many drugs have been developed to combat infection • Adolescents and young adults are at highest risk for contracting STIs