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How and why the heart goes wrong. What there is to go wrong. How and why the heart goes wrong. VALVES MUSCLE VESSELS ELECTRICS. How and why the heart goes wrong. MUSCLE VALVES VESSELS ELECTRICS. How and why the heart goes wrong. How and why the heart goes wrong.
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How and why the heart goes wrong VALVES MUSCLE VESSELS ELECTRICS
How and why the heart goes wrong MUSCLE VALVES VESSELS ELECTRICS
How and why the heart goes wrong • MUSCLE • Malformed • connections • holes • Cardiomyopathy • hypertrophic • dilated • restrictive • Hypertensive disease • Remodelling
How and why the heart goes wrong • VALVES • Congenital • malformed • Acquired • rheumatic fever • infective endocarditis • trauma • degenerative • floppy • senile calcification
Mitral stenosis Aortic stenosis Pulmonary stenosis Tricuspid stenosis Prosthetic stenosis Mitral regurgitation Aortic regurgitation Pulmonary regurgitation Tricuspid regurgitation Prosthetic regurgitation Heart Valve lesions
Aortic Stenosis - aetiology • Congenital – bicuspid valve • Acquired • Rheumatic • Senile/degenerative
How and why the heart goes wrong • VESSELS • Malformed • Atheromatous disease • stenosis • narrowing • myocardial ischaemia • angina • occlusion • blockage • myocardial infarction • dilatation • aneurysmal • dissection
How and why the heart goes wrong • ELECTRICS • Malformed • inadequate connection • excessive connection • Molecular • instability • Degenerative • Bystander • MI, infection, cardiomyopathy
AV node disease Complete (3rd degree) heart block
Mitral regurgitation – pathophysiology • Leaking mitral valve • LV emptying • LV filling • LV dilatation • LV stretch contractile failure • LA pressure • LA stretch • Atrial arrhythmia (atrial fibrillation) • Thrombo-embolic risk • stroke (cerebrovascular accident) • heart attack (myocardial infarct)
Mitral regurgitation – pathophysiology • Leaking mitral valve valve • LV emptying • LV filling • LV dilatation • LV stretch contractile failure muscle • LA pressure • LA stretch • Atrial arrhythmia (atrial fibrillation) electrics • Thrombo-embolic risk • stroke (cerebrovascular accident) • heart attack (myocardial infarct) vessels