App Name: DIYgenomics

1. App Name: DIYgenomics Prototype location: http://www.DIYgenomics.org/Sencha/Sencha.html DIYgenomics @DIYgenomics PO Box 61258 www.DIYgenomics.org Palo Alto, CA 94306 melanie@DIYgenomics.org 415-505-4426 laura@DIYgenomics.org

2. DIYgenomics highlights • Quality/functionality • Three data views, four levels of drill-down • HTML5 Technology/Web Standards Usage • Integrated web technologies (HTML5, CSS3, and webkit) with Sencha Touch consolidate three code bases (iOS, Android, and Web) into one • Innovation • Organizing genomic research into easily-understandable information linking genes to health and immediate action-taking • User experience • Usability testing identified three distinct user groups with diverse requirements

3. DIYgenomics mobile application • Provides general education to the public regarding personal genomics • Displays the markers reviewed for the top 20 health risk, drug response, and athletic performance conditions • Presents data in a manner that is relevant to laypersons and experts

4. 1. Quality/functionality • Three kinds of genomic data views are provided • Health risk, drug response, and athletic performance • Four levels of data drill-down are provided • Educational overview and side-by-side service comparison • Underlying research references and link to paper abstract

5. DIYgenomics prototype: three DIYgenomics app: integrated web separately maintained code bases technologies with Sencha Touch iOS Android 2. HTML5 Technology/Web Standards Usage • Integrated web technologies (HTML5, CSS3, and webkit) with Sencha Touch consolidate three code bases (iOS, Android, and Web) into one Web iOS, Android, and Web

6. 3. Innovation • DIYgenomics • conducts and organizes large amounts of genomic research • into chunks of easily-understandable information • educating individuals as to how genes are connected to health • and what personalized actions can be taken as a result • Application is provided as open-source, targeted to developers and for white-label use in clinical trials Example of the three views: health risk, drug response, and athletic performance

7. 4. User experience of DIYgenomics • App has been successfully prototyped to genome researchers • Requirements determined through one-on-one usability testing (15 people) and web-based surveys (35 responses) • Three distinct user groups with different requirements: • Layperson, health • Health and athletic • Genome researcher & • performanceoptimizer • decision maker1 • health professional • Education, clearly digestible information,service comparison, recommendations • Easily accessible technical information that can be verified and readily turned into personalized action-taking • Rapid information access, research references, custom configurability, personal data upload, search • 155 year old women are the biggest health decision makers in the US • Image credits: www.ehow.com, www38.homepage.villanova.edu

8. 15 Feb 2011 15 Jan 2011 31 Mar 2011 15 Dec 2010 1.1 1.0 Beta 3 Beta 2 Additional functionality roadmap • Private data upload of personal genome data files • Application-wide search functionality • Bookmarking, note-clipping • Application custom configuration and default configuration profiles choice at installation • Additional views: cosmetic product response, cancer, carrier status, aging, personality 1 2 3 4 4 1 2 3

9. DIYgenomics highlights • Quality/functionality • Three data views, four levels of drill-down • HTML5 Technology/Web Standards Usage • Integrated web technologies (HTML5, CSS3, and webkit) with Sencha Touch consolidate three code bases (iOS, Android, and Web) into one • Innovation • Organizing genomic research into easily-understandable information linking genes to health and immediate action-taking • User experience • Usability testing identified three distinct user groups with diverse requirements

10. Thank you! Team: Laura Klemme Melanie Swan DIYgenomics @DIYgenomics PO Box 61258 www.DIYgenomics.org Palo Alto, CA 94306 melanie@DIYgenomics.org 415-505-4426 laura@DIYgenomics.org