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Gene Identification: Diapause or Non-diapause in Drosophila

This presentation by Kate Steidle on December 2, 2003 explores the gene CG18370, focusing on its functions, biological processes, cellular components, and amino acid sequence in Drosophila. The discussion includes comparisons with other species like Anopheles, Danio rerio, and Homo sapiens.

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Gene Identification: Diapause or Non-diapause in Drosophila

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  1. BIOINFORMATICS Presentation by Kate Steidle December 2, 2003

  2. Gene Identification

  3. Diapause or Non-diapause?

  4. Centrosomin -Characteristics: Centrosomal protein; 150 kDa; found in Drosophila • Functions: Major centrosomal protein required for the assembly and function of the centrosome at mitosis • Biological Processes: central nervous system development; centrosome cycle; female meiosis chromosome segregation; midgut development; peripheral nervous system development • Cellular Components: Centrosome; myosin

  5. Amino Acid Sequence • >CG18370-MDQSKQVLRDYCGDGNGTCASSLKEITLIETVTSFLEENGAAEIDRRVLRKLAEALSKSIDDTSPGALQDVTMENSYASFDVPRPPGGGNSPLPSQGRSVRELEEQMSALRKENFNLKLRIYFLEEGQPGARADSSTESLSKQLIDAKIEIATLRKTVDVKMELLKDAARAISHHEELQRKADIDSQAIIDELQEQIHAYQMAESGGQPVENIAKTRKMLRLESEVQRLEEELVNIEARNVAARNELEFMLAERLESLTACEGKIQELAIKNSELVERLEKETASAESSNANRDLGAQLADKICELQEAQEKLKERERIHEQACRTIQKLMQKLSSQEKEIKKLNQENEQSANKENDCAKTVISPSSSGRSMSDNEASSQEMSTNLRVRYELKINEQEEKIKQLQTEVKKKTANLQNLVNKELWEKNREVERLTKLLANQQKTLPQISEESAGEADLQQSFTEAEYMRALERNKLLQRKVDVLFQRLADDQQNSAVIGQLRLELQQARTEVETADKWRLECVDVCSVLTNRLEELAGFLNSLLKHKDVLGVLAADRRNAMRKAVDRSLDLSKSLNMTLNITATSLADQSLAQLCNLSEILYTEGDASHKTFNSHEELHAATSMAPTVENLKAENKALKKELEKRRSSEGQRKERRSLPLPSQQFDNQSESEAWSEPDRKVSLARIGLDETSNSLAAPEQAISESESEGRTCATRQDRNRNSERIAQLEEQIAQKDERMLNVQCQMVELDNRYKQEQLRCLDITQQLEQLRAINEALTADLHAIGSHEEERMVELQRQLELKNQQIDQLKLAHSTLTADSQITEMELQALQQQMQEIEQLHADSVETLQSQLQKLKLDAVQQLEEHERLHREALERDWVALTTYQEQAQQLLELQRSLDYHQENEKELKQTLVENELATRALKKQLDESTLQASKAVMERTKAYNDKLQLEKRSEELRLQLEALKEEHQKLLQKRSNSSDVSQSGYTSEEVAVPMGPPSGQATTCKQAAAAVLGQRVNTSSPDLGIESDAGRISSVEVSNAQRAMLKTVEMKTEGSASPKAKSEESTSPDSKSNVATGAATVHDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNVRSNMENEL

  6. Conserved Domains

  7. Clustalw • Drosophila - Fruitfly • Anopheles - Pest • Danio rerio – Zebrafish • Homo sapiens - Human

  8. CG18370 clustalw.doc

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