1 / 5

Research Focus: Searching for Novel Riboswitches in Newly Sequenced Genomes

Biological Application: RNAs. Research Focus: Searching for Novel Riboswitches in Newly Sequenced Genomes. Danny Barash † Department of Computer Science Ben-Gurion University † email: dbarash@cs.bgu.ac.il. With TPP. What are Riboswitches?. Terminator.

jody
Download Presentation

Research Focus: Searching for Novel Riboswitches in Newly Sequenced Genomes

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Biological Application: RNAs Research Focus: Searching for Novel Riboswitches in Newly Sequenced Genomes Danny Barash† Department of Computer Science Ben-Gurion University †email: dbarash@cs.bgu.ac.il Bioinformatics

  2. With TPP What are Riboswitches? Terminator Vitamin B1 biosynthesis in bacteria: TPP-mediated attentuation control: E. Nudler and coworkers: (Mironov et al., Cell, 2002) Thiamine pyrophosphate are the metabolites that alter conformation. Aptamer Bioinformatics

  3. Without TPP What are Riboswitches? Anti-terminator Vitamin B1 biosynthesis in bacteria: TPP-mediated attentuation control: E. Nudler and coworkers: (Mironov et al., Cell, 2002) Thiamine pyrophosphate are the metabolites that alter conformation. Aptamer Bioinformatics

  4. Searching for riboswitches ineukaryotes by their aptamer Sequence is not enough, need structure considerations! Bioinformatics

  5. Searching for riboswitches ineukaryotes by their aptamer (Cohen et al., In Silico Biology, 2008) – a riboswitch in plants? Our 3-stem junction candidate in plants Known consensus in bacteria Bioinformatics

More Related