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Tissues and a Introduction to the Epithelium. Levels of Organization. atoms→molecules→organelles→cells →tissues. In the body, tissues can be classified into the following functions: Epithelial – cover 1 Connective – support 2 Movement – muscle 3 Control – nervous 4.
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Levels of Organization atoms→molecules→organelles→cells →tissues
In the body, tissues can be classified into the following functions: Epithelial – cover 1 Connective – support 2 Movement – muscle 3 Control – nervous 4
Epithelial Tissues • Epithelial cells can be classified into 2 types, those that cover surfaces and cavities and those that form a glandular function.
Epithelial tissues have the following functions: • Protection • Absorption • Filtration • Excretion • Secretion • Sensory Reception
Characteristics of epithelial tissues: • Epithelial cells have an upper or free surface.
Characteristics of epithelial tissues: • Epithelial cells have an upper or free surface. • This is known as the Apical Surface
Polarity • The apical surface can be modified by microvilli or cilia. • Microvilli are seen with cells associated with absorption.
Polarity • The microvilli can be so thick that it can be described as a brush boarder.
Polarity • The bottom side of the epithelial cell is called the basal surface. • It is supported by a non cellular, adhesive sheet called the basal lamina.
Epithelial cells have contact with each other. These lateral contacts are the desmosomes and tight junctions. Specialized Contacts
Specialized Contacts • The tight junction forms an impermeable junction between each cell and thus prevents diffusion between the cells.
Specialized Contacts • The desmosomes help hold the cell’s shape with anchoring junctions scattered between each cell.
Connective Tissue Support • The basilar surface attached to a connective tissue net work. • There are two parts. The first is the basal lamina secreted from the epithelial cell. • The second is the reticular lamina that is made of collagen which is produced by fibroblasts.
Connective Tissue Support • Together the basal lamina and reticular lamina form the basement membrane. • This forms the foundations which anchor the epithelial cells.
Avascular but Innervated • Epithelial cells do not have a blood supply • They depend on diffusion for the delivery of nutrients and removal of wastes. • They do have a nerve supply, innervated, for sensory function.
Regeneration • Do to their protective function; epithelial cells need to be continually replaced. • Mitotic figures are not uncommon.
Cancer • Many cancers are of epithelial origin. • The greater the mitotic index, the greater the chance of cancer.
Cancer Types • Lung cancer caused by smoking typically starts in the bronchial epithelium