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Global Disease Detection Operations Center

Global Disease Detection Operations Center. Ray R. Arthur, PhD Director, Global Disease Detection Operations Center Center for Global Health, Centers for Disease Control and Prevention. Global Disease Detection Program CDC Contribution: W orldwide Surveillance & Response.

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Global Disease Detection Operations Center

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  1. Global Disease Detection Operations Center Ray R. Arthur, PhD Director, Global Disease Detection Operations Center Center for Global Health, Centers for Disease Control and Prevention

  2. Global Disease Detection Program CDC Contribution: Worldwide Surveillance & Response • Detection and verification of international disease events and threats • Operational support for rapid deployment of CDC assets and field teams • US compliance with IHR • CDC’s liaison with Global Outbreak Alert and Response Network (GOARN) • GDD Operations Center Team • Director:PhD Microbiologist/Virologist • Analysts (4): Med Epi, Vet Epi, PhD Epi • Emergency Coordinator 2

  3. International Outbreak Alert & Response Epidemic Intelligence Framework • Indicator-based surveillance • Event-based surveillance “Surveillance” systems • Event monitoring Data Events CollectAnalyseInterpret CaptureFilterValidate • Domestic • Media review • EI focal points • International • Info scanning tools • Distribution lists • International agencies • Identified risksMandatory notification • Laboratory surveillance • Emerging risks • Syndromic surveillance • Mortality monitoring • Health care activity monitoring • Prescription monitoring • Non healthcare based • Poison centres • Behavioural surveillance • Environmental surveillance • Veterinary surveillance • Food safety/Water supply • Drug post-licensing monitoring Signal Assess Disseminate Public health Alert • Early Warning and Response System • Rapid inquiries (Enternet) • E-Alerts (Eurosurveillance) • Intern. Health Regulations (WHO) • Threat bulletin (ECDC) • WEB Investigate Control measures Source: ECDC

  4. International Outbreak Alert & Response Screen sources of epidemic intelligence • Capture disease event Information • CDC programs (US & overseas), WHO, Media reports (Argus, GPHIN), ProMED, OIE, FAO, Classified Potential international public health Importance? Enter in database & report Response 4

  5. Internet Event-based Surveillance Systems Available systems

  6. International Outbreak Alert & Response Project Argus: Media “tipping” Analysis: • 3 Chief Analysts • 4 deputy Chief Analysts • 8 Senior Analysts • 30 Analysts Reading Fluency: • ~40 Languages Statistics* • 228 Countries • >10,000 Sources • 335 Million articles archived *June 2006- Jan. 2010

  7. International Outbreak Alert & Response Screen sources of epidemic intelligence • Analyse and assign “threat” level • (GDD analyst and Subject Matter Experts) • Serious impact on public health • Unusual or unexpected • Significant risk for international spread • Significant risk for trade and travel restrictions Potential international public health Importance? Enter in database & report Response

  8. International Outbreak Alert & Response Screen sources of epidemic intelligence Potential international public health Importance? YES Enter in database & report • Enter event into Event Analysis Management System • Disseminate Event information • CDC Programs • USG Agencies Response

  9. What We are Watching Now

  10. International Outbreak Alert & Response Screen sources of epidemic intelligence Potential international public health Importance? Enter in database & report Malawi, 2009 • Fund and facilitate response to disease event • Global Outbreak Alert and Response Network (GOARN) and/or Bilateral Response

  11. Global Disease Detection Operations Center: International Outbreak Alert & Response • Diseases: Ebola, Marburg, H1N1, H5N1 Influenza, Cholera, Monkeypox, Plague, RVF, Zika, DEG, Typhoid, Lead poisoning, and others • Deploying CDC expertise • Outbreak responses 50 • 28 Countries • ~$ 4-5 million since 2006 * Acute Hemorrhagic Fever Syndrome, Acute GI Syndrome, Acute Neurological Syndrome, Aflatoxin, E. coli, Fungal Disease, H1N1, HEV, Lead Poisoning, Legionellosis, Liver Disease, Measles, Meningitis, Q Fever

  12. IMPACT: Early Warning, Alerting for Response Coordination of investigations where etiology is unknown Ad hoc reports to CDC staff in the US and at international locations Rapid assessments from the field Transporting samples Expert analysis and prediction of disease agent Through refined methodologies, systems and protocols: Kasai Occidental, Democratic Republic of Congo, Sept. 2007 12

  13. Summary: GDD Operations Center Housed in Emergency Operations Center (EOC) Consolidating international outbreak information from sources inside and outside of CDC Systematically conducting risk assessments, reporting and responding to infectious disease events in support of IHR Adding value by leveraging technical expertise of CDC programs Facilitating rapid responses via emergency response outbreak contingency funds

  14. Thank You http://www.cdc.gov/globalhealth/GDD/ GDD-Outbreak@cdc.gov

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