1 / 15

hTERT cell line 에 PAH 노출 후 molecular study (cell count, Viability, Copy number variation 등 )

실험계획. hTERT cell line 에 PAH 노출 후 molecular study (cell count, Viability, Copy number variation 등 ) Leukemia cell line - THP-1 cell line 에서 발굴된 Protein ( Prelamin -A/C, Poly [ADP-ribose] polymerase 1) 의 mRNA 수준에서 expression study

juana
Download Presentation

hTERT cell line 에 PAH 노출 후 molecular study (cell count, Viability, Copy number variation 등 )

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 실험계획 hTERT cell line에 PAH 노출 후 molecular study (cell count, Viability, Copy number variation등) Leukemia cell line - THP-1 cell line 에서 발굴된 Protein (Prelamin-A/C, Poly [ADP-ribose] polymerase 1)의 mRNA 수준에서 expression study - Western blotting을 이용한 prelamin-A/C, poly [ADP-ribose] polymerase 1 Protein 분석 3. In vivo Zebrafish model - Western blotting을 이용한 LMNA, PARP-1 Protein 분석 - Protein (Prelamin-A/C(LMNA), Poly [ADP-ribose] polymerase 1 (PARP-1))의 mRNA 수준에서 expression study 4. SETBP1 mutation in MDS/MPN Patients

  2. vimentin Vimentin plays a significant role in supporting and anchoring the position of the organelles in the cytosol. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

  3. talin-1 Talin-1 is a protein that in humans is encoded by the TLN1gene. This gene encodes a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts.

  4. SETBP1 mutations in MDS/MPN

  5. Nature Genetics

  6. Nature Genetics

  7. 607bp M 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 M 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30

  8. zebrafishmtDNAcytochrome b gene and β-actin 54hpf

  9. 78hpf

  10. 54hpf

  11. 78hpf

  12. 54hpf 78hpf

More Related