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KNOWLEDGE TRANSFER BEST PRACTICES BETWEEN APEC ECONOMIES

Mechanisms for effective knowledge transfer in agriculture will be discussed at the APEC conference in Lima, Peru. The event will showcase best practices and strategies for successful knowledge transfer. Don't miss this opportunity to learn from experts in the field.

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KNOWLEDGE TRANSFER BEST PRACTICES BETWEEN APEC ECONOMIES

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  1. KNOWLEDGE TRANSFER BEST PRACTICES BETWEEN APEC ECONOMIES LIMA, PERU 13 – 15 June 2018 Mechanisms to an effective knowledge transfer in the agriculture sector Monica AlandeteSaez June 14 2018

  2. University of California A Ten Campus System with Broad Impact in Science and Innovation • ~26,000 Publications • in Life and Health Sciences • 1,776 Invention Disclosures • 4,118 Active US Patents • 61 Start-up Companies Formed • $119.2 Million • in Licensing Revenue - 2012 ResearchInvestment $3.35 Billion 10 campuses; all research-intensive 17,000 faculty 220,000 students System-wide policies & legal oversight Largely decentralized decision-making $46.3 Billion ~430,000 jobs Economic Impact

  3. Technology Transfer Program is De-Centralized in the University of California Economy of scales to control risks Close to inventors and regional companies

  4. University of California, Davis – from its roots Research Awards ($ millions) • Ranked 7thamong public research universities nation-wide • 5thamong U.S. universities in the number of international scholars (“Open Doors 2010 Report on International Educational Exchange” by the Institute of International Education) • 2ndamong universities in teaching and research in Agricultural and Forestry (QS World University Rankings) • 1. WageningenUniversity • 2. University of California, Davis • 3. Cornell University • 4. University of Wisconsin, Madison • 5. Texas A&M University $750 $300 2001-01 2011-12

  5. Research: essential input to innovation But the IDEA is not innovation – needs “translation” Discovery Innovation

  6. What is one of the top innovations of the 20th century? The Idea N2 + 3H2 2 NH3 + ΔH Professor, Ruprecht Karl University of Heidelberg

  7. What is one of the top innovations of the 20th century? The invention

  8. What is one of the top innovations of the 20th century? The innovation Thefactory / city of Oppau: 36,000 mT of ammonium sulfate. Process Haber-Bosch Thefertilizersgeneratedfromtheammoniumproducedbythe Haber-Bosch process are responsibleforsustaining a third of theworld'spopulation. Half of theprotein in the human bodyismadefromthenitrogenfixedbythe Haber-Bosch..

  9. What is one of the top innovations of the 20th century? The Idea

  10. What is one of the top innovations of the 20th century? The Invention

  11. What is one of the top innovations of the 20th century? The Innovation

  12. What is the innovation? Process of “translating” an idea or invention into a product or service that creates value. “The creative process (or innovation process) does not end with the idea – it only begins with the idea.” John Arnold, Stanford Engineering The translational process between the idea and the innovation is not easy, is not automatic and requires expertise and a culture that is not present in the majority of universities.

  13. Invention Capital investment Technology Transfer Office Regulation IP Management Manufacturing, etc. Technology Transfer –Public Private Partnerships

  14. Technology Transfer Model Royalties/ Equity Issued Patent Invention Disclosure License Agreement Patent Application University/Technology Transfer Office

  15. Public institutions can be a source of Innovation Business Development Regional EconomicDevelopment

  16. Building a culture for innovation - Leadership counts “California's economic rise is closely tied to the rise of its research universities. New industries have been invented, new products have been developed and new medical techniques have been invented to both save lives and enhance their quality.” - UC President Atkinson Knowledge Transfer Best Practices Between APEC Economies. Lima, Peru: 13 - 15 June 2018

  17. Legal Framework to Manage IP • Created clarity about IP ownership • Localized licensing of IP near researcher/inventor • Created incentives to build technology transfer infrastructure FocusonIntellectualProperty Bayh-Doleact (1980) allowsinstitutionstopatentdiscoveriesmadewithpublicfunds

  18. Patentsownedbyuniversities in relation to total patents in US Bayh-Dole Act, 1980

  19. Legal Framework to Manage IP Bayh-DoleAct > 30 years • Universities may elect title to inventions developed through Federal funding • Universities must file patents on inventions they elect • University must have written agreements with faculty and staff requiring disclosure and assignment of inventions • University must share a portion of revenue with inventors • Excess revenue must support research and education • Government retains non-exclusive license to the invention • Government retains march-in rights • Requirement for substantial US manufacture

  20. IP policyUniversity of California (1997)

  21. Infrastructure to support technology transfer & industry collaborations Deliberate and strategic IP management to identify best innovative path Founded 2004 Technology Transfer Services (lawyers and scientists) Business Development Services (MBAs and entrepreneurs) Staff of 22 for a research base of >750 M

  22. Commercialization strategies Strawberries – non-exclusive, worldwide partners Trehalose – exclusive pharma license; Arete therapeutics– start-up with equity + royalties Genetic resources – tangible property bailments with reach – through to product royalties

  23. Compositions and methods for reducing H2S levels in fermented beverages using improved yeasts

  24. Renaissance Yeast 2007 2008 2012 2010 International protection strategy

  25. RenaissanceYeast • Protection Cost • Total investment in the prosecution of 1 patent family with 2 patents: • At least $ 380,000, not counting the maintenance costs of the patents granted in each territory! • Patents granted: US, BR, AU, NZ, CN, JP, GE, SP, IT, FR, IN, VN, RU, • Pending Applications: CA • The University was free to protect in the territories in which the licensee was not interested-

  26. UC Davis Strawberry Licensing Program -leader in California & World • Strawberry Industry in California:$2.2 B • Represent 75% California production • Leader, position #1, global level • In 25 years, Spanish Strawberry Industry grew up to $1B • Transfer of varieties & know-how • 70-90% UC Davis varieties

  27. Licensing Program Objectives • Benefit California industry with development of new varieties • IP Protection -US & Global • Create a global licensing system in production areas • Provide funds to continue selection of new varieties D. France Strawberry Grower Santa Maria, CA

  28. Variety improvement components • Yield • Transport and shelf life • Pick speed – labor 50% of total operating costs – plant type • Disease resistance • Production windows • Appearance and flavor

  29. IP Protection Strategy Worldwide • US - Plant Patent • Ex-US – UPOV PBR where available • 20 – 25 countries per variety • 560 active strawberry IP filings

  30. Worldwide Fruit Production UC Varieties - Examples

  31. Licensing Strategies Domestic Market – US/Canada International Markets • *Direct* licence with nurseries • Non-exclusive terms • propagation of plants • sell to fruit producers • sell to licensed propagators • Reduced royalties in California • Provide funds to continue selection of new varieties • *Direct* licence with Master licensees- not a nursery or grower • Exclusive terms • By territory • Sublicense nurseries • Control unauthorized propogation • Royalty-share with UC • Higher royalties

  32. Royalty Structure Worl $ 16 per 1000 plants ~$3.4M Royalties United States $ 9 per 1000 plants ~$ 100,000 Royalties California Licensing Program Anually $8-10M Managed by 2.5 FTE $8 per 1000 plantas ~ $ 3.2 M Royalties

  33. THANK YOU MónicaAlandete-Sáez PhD.Director Analysis & Education PIPRA/UC Davis Science & Tech Transfer Associate UC Davis-Chile Innovation Center malandete@ucdavis.edu www.pipra.org www.ucdavischile.org Knowledge Transfer Best Practices Between APEC Economies Lima, Peru.13 - 15 June 2018

  34. Genetic resources and biological materials Terms of Use UC DAVIS/PHAFF YEAST CULTURE COLLECTION Non-Commercial Research License Agreement These YEAST STRAINS are the property of The Regents of the University of California as represented by its Davis campus (“THE REGENTS”) or third party donors (“DONORS”) who have donated YEAST STRAINS for distribution to companies, institutions, universities and other entities (“RECIPIENTS”). Use of the YEAST STRAINS is subject to the USAGE RESTRICTIONS below. For other uses, including commercial use, please contact THE REGENTS for appropriate licenses. THE REGENTS and/or DONORS retain ownership o

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