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Cell Clock, Mitosis, & Cancer

Cell Clock, Mitosis, & Cancer. Chapter 8 (Do Ch 8 outlines & vocab!) Chapter 12 in Campbell text. Cell Clock. Definition: How stem cells spend their time G1, S, G2 = Interphase (growth, DNA synthesis, more growth) Mitosis = cell division G0 = specialized cells. Mitosis.

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Cell Clock, Mitosis, & Cancer

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  1. Cell Clock, Mitosis, & Cancer Chapter 8 (Do Ch 8 outlines & vocab!) Chapter 12 in Campbell text

  2. Cell Clock • Definition: How stem cells spend their time • G1, S, G2 = Interphase (growth, DNA synthesis, more growth) • Mitosis = cell division • G0 = specialized cells

  3. Mitosis • Mitosis = cell division of autosomal cells; Meiosis = cell division of sex cells • PMAT = prophase, metaphase, anaphase, telophase • What happens at each stage? http://www.cellsalive.com/mitosis.htm

  4. Actual Cell Pictures of Mitosis • Picture: • 1: Prophase • 2: Metaphase • 3: Anaphase • 4: Telophase • Let’s do the MITOSIS DANCE!

  5. Cancer • Every minute, ten million cells divide in the human body. Normally, cell division, accompanied by growth and specialized development, takes place in an orderly pattern. But when a cell becomes malignant, it acts in profoundly abnormal ways.

  6. Cancer Development • Cancer develops from a single cell that has undergone mutations in its DNA. • Instead of maturing normally and dying, cancerous cells reproduce without restraint. • They never stop dividing, and they fail to mature. (Immortal)

  7. Causes of Cancer • Ultraviolet radiation • X-rays • Drugs, Smoking, and Alcohol • Industrial chemicals • Diet and obesity • Genetics and Heredity • Stress • Viruses

  8. Smoking Attributable RiskPercent of Deaths (1991)

  9. Tobacco • Tobacco is the single greatest cause of cancer worldwide (preventable!) • Many poisonous substances: 44 Carcinogens (hydrogen cyanide, carbon monoxide, formaldehyde, nicotine, strychnine, arsenic, benzenes, nitrous-amine compounds…) • http://www.pbs.org/wgbh/nova/cigarette/nicotine.html

  10. Search for a Safer Cigarette? • Elimination of tobacco is the single most important step to our winning the war against cancer. • Let’s watch a video!

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