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Diamond-like Carbon Coating for Bio-medical Implant Materials

Acknowledgement. Dr. R. Hauert (EMPA, Switzerland)for valuable discussion and providing me the presentation materials on this issue. Prof. Jeong-Ku Kim (SKKU, Korea) for corrosion test in body fluid conditionProf. In-Seop Lee (Yonsei Univ., Korea) for tribological test of DLC coated Ti alloys in body fluidProf. Hyeonee Kim (SNU, Korea) for cell attachment and hemocompatbility testProf. R. Wang (UBC, Canada) for mechanical stability testMr. Sejun Park, Mr. Heon-Woong Choi and Ms. Youngjin31447

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Diamond-like Carbon Coating for Bio-medical Implant Materials

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    1. Diamond-like Carbon Coating for Bio-medical Implant Materials Kwang-Ryeol Lee Future Technology Research Division Korea Institute of Science and Technology krlee@kist.re.kr http://diamond.kist.re.kr/DLC

    2. Acknowledgement Dr. R. Hauert (EMPA, Switzerland) for valuable discussion and providing me the presentation materials on this issue. Prof. Jeong-Ku Kim (SKKU, Korea) for corrosion test in body fluid condition Prof. In-Seop Lee (Yonsei Univ., Korea) for tribological test of DLC coated Ti alloys in body fluid Prof. Hyeonee Kim (SNU, Korea) for cell attachment and hemocompatbility test Prof. R. Wang (UBC, Canada) for mechanical stability test Mr. Sejun Park, Mr. Heon-Woong Choi and Ms. Youngjin Lee Financial Support from Ministry of Science and Technology of Korea

    3. Bioimplant Materials

    4. Required Surface Properties Biological Compatibility Nontoxic, Noncarcinogenic, Noninflammatory Chemical Compatibility Corrosion Resistance Mechanical Compatibility Surface Hardness, Wear Resistance

    5. Contents Introduction to DLC Blood Contacting Applications Stents, Heart valves, Flow Accelerators Load Bearing Applications Hip Joints, Knee Joints, Artificial Disk Summary and Technical Issues

    6. Diamond-like Carbon : DLC Amorphous Solid Carbon Film Mixture of sp1, sp2 and sp3 Hybridized Bonds High Content of Hydrogen (20-60%)

    7. DLC: A Group of Carbon Matl

    8. Properties of Solid Carbon

    9. Applications of DLC

    10. Contents Introduction to DLC Blood Contacting Applications Stents, Heart valves, Flow Accelerators Load Bearing Applications Hip Joints, Knee Joints, Artificial Disk Summary and Technical Issues

    11. Blood Contacting Applications

    12. Protein Adsorption on DLC

    13. Excellent Hemocompatibility

    14. Excellent Hemocompatibility

    15. DLC Coated Stents

    16. Potentiodynamic Polarization

    17. DLC Coated Stents

    18. Evolution of Coating Failure

    19. DLC Coated Heart Valves etc.

    20. Contents Introduction to DLC Blood Contacting Applications Stents, Heart valves, Flow Accelerators Load Bearing Applications Hip Joints, Knee Joints, Artificial Disk Summary and Technical Issues

    21. Load Bearing Implants

    22. DLC Coating on Femoral Ball

    25. DLC/DLC or DLC/metal

    26. Hip Joints: in vivo Test

    27. Adhesive Wear in Body Fluid

    28. DLC Coated Artificial Joints

    30. Summary DLC film is not a specific materials but a group of amorhpous carbon materials Blood Contacting Applications Good hemocompatibility DLC Coated stents, heart valves, blood pumps are now available in the market. Artificial Joints Application Needs an improved test method to obtain clinically relevant results. DLC/DLC or DLC/metal combinations show more promising results than other combinations.

    31. Technical Issues Careful consideration on the DLC film itself is required, because the DLC film is not a specific material. Stability of DLC coating in body fluid condition is one of the most critical issues for the biomedical applications. Stents Stability of the coating with respect to the plastic deformation Interface design would be helpful to increase the reliability. Artificial Joints Characterization of the coating under an adequate test condition Does it really reduce the PE debris? Is it possible to have new design such as DLC/DLC or DLC/metal? Stability of the coating during sliding in body fluid condition Need tight control of the substrate surface

    32. Diamond-like Carbon Coating for Bio-medical Implant Materials Kwang-Ryeol Lee Future Technology Research Division Korea Institute of Science and Technology krlee@kist.re.kr http://diamond.kist.re.kr/DLC

    33. Cells in contact with DLC

    34. Cell Growth Behavior

    35. Protein adsorption on Ti-DLC Adsorption of human plasma proteins on a-C:H/Ti Chromatographic analysis of the proteins. Molecular weight marker is indicated on the left side.

    36. Bone Marrow Cells (BMC)Bone Marrow Cells (BMC)

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