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EBM process – 4 steps. ······················································································. Question? Search for information Critical review Application. The main step. ······················································································.
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EBM process – 4 steps ······················································································ • Question? • Search for information • Critical review • Application
The main step ······················································································ Search for information 1. Search wide (high sensitivity) 2. Limit irrelevant hits (high specificity) 3. Use a good hit to find other relevant articles
Choose the right database ······················································································ Search for information in this order: 1. The Cochrane Library 2. Mega-search engine (SUMSearch) 3. Other secondary databases (BestBets) 4. Clinical guidelines (Clinical Evidence) 5. …first now MEDLINE (PubMed)
Some addresses ······················································································ www.thecochranelibrary.com http://sumsearch.uthscsa.edu www.tripdatabase.com www.scirus.com www.bestbets.org www.clinicalevidence.com www.pubmed.gov
Evaluation of scientific quality ······················································································ Why? - Purpose In what way? - Design How good? - Quality How large? - Effect size How accurate? - Reliability So what? - Relevance/Importance
The level of evidence ······················································································ Level Meaning Background A Good Meta-analysis, syst. reviews. large RCT B Moderate Small RCT, cohort-, case- control- and cross sectional studies C Low Case reports, expert opinion D None No studies available