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Abstract

Abstract. Demographic Variables. Age 64-68 Gender Male and female Diagnosis Sepsis or septic shock Hypotension Elevated lactate level. Research Design. Specific design of study Cohort Study Interventions Use and insertion of invasive monitoring equipment in ED

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Abstract

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  1. Abstract

  2. Demographic Variables • Age • 64-68 • Gender • Male and female • Diagnosis • Sepsis or septic shock • Hypotension • Elevated lactate level

  3. Research Design • Specific design of study • Cohort Study • Interventions • Use and insertion of invasive monitoring equipment in ED • Monitoring of hemodynamic parameters such as: • central venous pressure (CVP) • arterial pressure (MAP) • continuous venous oxygen saturation (ScvO2) • Group • Completed protocol • Failed to complete protocol

  4. Sample and Setting • Setting • Large urban tertiary-care hospital • Emergency Department (ED) • Medical Intensive Care Unit (MICU) • Inclusion criteria • Patients admitted to the ED with severe sepsis and hypotension or elevated lactate level • Exclusion criteria • Refusal of central line insertion • Documented contraindication to central line insertion • Did not survive long enough to undergo 6 h of EGDT • Patients not a candidate for aggressive treatment

  5. Sample and Setting (cont.) • Method used • Statistical method • Sample size • Independent-samples t test over both the 3-month and the 6-month period. • p value based on an independent-samples t test • Mortality rate • The eligible patients had an overall in-hospital mortality rate of 30.5% with a mean APACHE II score of 29. • Refusal to participate number and percentage • 2 patient refused CVP • 19 total did not meet criteria • Institutional review board • Rhode Island Hospital • Consent • Waived

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