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Susceptibility Weighted MRI and Cerebrovascular Disorders

Susceptibility Weighted MRI and Cerebrovascular Disorders. Fony Y Tsai, Hung-Wen Kao, Yu-Kun Tsui, Anton H Hasso and Fred Greensite, UC Irvine Medical Center, Orange, Ca. Method and Materials.

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Susceptibility Weighted MRI and Cerebrovascular Disorders

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  1. Susceptibility Weighted MRI and Cerebrovascular Disorders Fony Y Tsai, Hung-Wen Kao, Yu-Kun Tsui, Anton H Hasso and Fred Greensite, UC Irvine Medical Center, Orange, Ca

  2. Method and Materials • All patients underwent MRI with 12 channel head coil in 1.5T(Avanto,Siemens,Erlangen,Germany)and 3T(Trio,Siemens,Erlangen,Germany). • Parameters of SWI: • 1.5T:TR:49ms,TE40msFlip angle15,bandwidth 80kHz,slice thickness 2mm,64slices in a single slab,matrix size177x256,acquistion time 3min&59s with iPAT factor-2. • 3T:Tr27ms,TE29ms,Flip angle15,bandwidth 120kHz,slice thickness 2mm,64slices in a single slab, matrix size182x256,acquisition time 3min&22s with iPAT factor-2 • All images obtained in axial plane • The phase,magnitude,SWI and minIP images were uploaded to PACS system.

  3. Method and Materials • Retrospectively reviewed 903 patients from July 2008 to July 2010. • Among those 595 patients who had varied cerebrovascular diseases were reported in our previous study excluded • 299 ischemic stroke,7 cardiac arrested with cessation of cerebral circulation and 2 chronic venous hypertension • Gender ratio: male to female:162 to 146 • Age: mean ae of all patients:65.4 and mean female is 69.1 and mean male age is 62.6. • 118 patients had complete pre and post-treatment CT,MRI with SWI. • 32 of 118 were excluded from motions and artifacts • 86 stroke patients and 9 others were evaluated in this series.

  4. Result of Stroke Patients • 4 patients: vertebral arterial disease • 7 patients: posterior cerebral arterial occlusion • 11 patients: internal carotid arterial thrombosis • 21 patients: diffused atherosclerosis • 2 patients: anterior cerebral arterial disease • 42 patients: middle cerebral arterial thrombosis • 23 patients had negative on SWI from small infarction on DWI • 56 patients had early sign of infarction on CT,CT finding did not accord with SWI • 63 patients had varied degree of abnormal hypointense vessel on SWI.

  5. Cases Presentations Case 1 28/male acute left side weakness, history of chronic headache without definite etiology

  6. CT,T1&DWI

  7. Flair&contrast

  8. Venous Pressure GradientIt was double SSS>SS Venous hypertension

  9. Case Presentation Case 2 52/F acute confusion with stomach Flu, Suddenly lapsed to coma, upon arrival to UCI from transferring, unresponsive.

  10. Initial CT

  11. arrival CT

  12. Case Presentation Case 3 55/M presented with acute left side weakness history of hypertension and hyperlipdemia

  13. PWI/MTT

  14. SWI

  15. Case Presentation Case 4 73/F presented with acute left side weakness with Aggrenox, history of TIA and hypertension

  16. Initial MRI DWI/Flair

  17. Flair,PWI/MTT

  18. PWI/ dfV

  19. MRA and Cerebral Angiogram

  20. Follow-up MRA &DWI

  21. Follow-up Flair

  22. Case Presentation Case 5 43/M presented with expressive aphasia, right homonymous hemianopsia and right side weakness, worse on upper extremity.

  23. Case Presentaion Case 6 56/M sudden lost his right eye vision and left side weakness, History of hypertension and recent Myocardial Infarction

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