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the brain. Honors Anatomy & Physiology f or copying. Brain: unremarkable appearance ~ 3 lbs 4 major regions. 1. Cerebral Hemisphere. right & left connected by large fiber tract: corpus callosum cover most of other 3 parts
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the brain Honors Anatomy & Physiology for copying
Brain: unremarkable appearance ~ 3 lbs 4 major regions
1. Cerebral Hemisphere • right & left connected by large fiber tract: corpus callosum • cover most of other 3 parts • surface: elevated ridges = gyriseparated by shallow grooves = sulci • Fissures deeper grooves separate regions of brain
Longitudinal Fissure • separates cerebral hemispheres • other fissures separate brain into lobes
Ventricles of the Brain • spaces in brain filled with CSF • connected to subarachnoid space (around brain & spinal cord) and central canal of spinal cord
Somatic Sensory Area • parietal lobe posterior to central sulcus • receives impulses from sensory receptors (not special senses), interprets them • pain recognition • temperature • light touch
Primary Motor Area • anterior to central sulcus in frontal lobe • major voluntary motor tract
Occipital Lobe • visual area
Temporal Lobe • auditory & olfactory areas
Frontal Lobe • Brocca’s Area: ability to speak • @ base of precentralgyrus (usually only on left side) • injury inability to correctly vocalize words
Lobe Functions • anterior frontal lobe: higher intellectual reasoning • complex memories: frontal/ temporal lobe • all facets of speech: occipital/temporal/parietal lobes
Basal Nuclei • gray matter in brain that is NOT in cerebral cortex • functions: help regulate voluntary motor activity by modifying instructions sent to skeletal muscle by primary motor cortex
Diencephalon • sits atop brain stem • enclosed by cerebral hemispheres • major parts: • Thalamus • Hypothalamus • Limbic system • Epithalamus
Thalamus • relay station for sensory impulses passing thru to sensory cortex
Hypothalamus • ANS center • role in: • temperature control • water balance • metabolism
Limbic System • regulates autonomic & endocrine functions in response to emotional stimuli (“reacting” brain vs. cerebral cortex being “thinking” brain) • set level of arousal • motivation • reinforcing behaviors • rage, love, memory, empathy
Brain Stem • ~size of thumb in diameter & ~ 3 inches long • 3 parts: • midbrain • pons • medulla oblongata
Choroid Plexus • knots of capillaries w/in each ventricle • produce & secrete CSF (cerebral spinal fluid)
Midbrain • smallest, uppermost part of brain stem • cerebral aquaduct: tiny canal that runs thru midbrain connecting 3rd & 4th ventricles • contains reflex centers for vision, hearing
Pons • “bridge” • rounded structure that protrudes below midbrain • contains apneustic (produces deep, prolonged inspirations) & pneumotatic center (inhibits inspiration)
Medulla Oblongata • most inferior part of brain stem • inferior border merges into spinal cord • centers: heart rate, BP, breathing, swallowing, vomiting
Cerebellum • large, cauliflower-like • projects dorsally from under occipital lobe • 2 hemispheres • convoluted surface • provides precise timing for skeletal muscle activity • Controls balance & equilibrium
Traumatic Brain Injuries • Head injuries are leading cause of accidental death in USA. • Concussion: dizziness, “see stars”, briefly lose consciousness; No permanent brain damage • Contusion: result of marked tissue damage. Cerebrum: may maintain consciousness Brainstem: coma • Cerebral Edema: swelling of brain due to inflammatory response to injury/ initially conscious neuro signs deteriorate (think edema or hemorrhage)
Cerebrovascular Accident(CVA) • stroke • 3rd leading cause of death in USA • occur when blood circulation to brain is interrupted • vessel could be blocked (temporary or permanent) or hemorrhaging
CVA • characterized by: • abrupt onset of persisting neurological symptoms that arise from destruction of brain tissue common causes: • intracerebral hemorrhage • emboli • atherosclerosis of cerebral arteries
CVA Risk Factors hypertension hypercholesterolnemia heart disease narrowed carotid arteries hx of TIAs (transient ischemic attacks) diabetes smoking obesity excessive alcohol intake
CVA Treatments • Thrombolytic: • clot-dissolving drug: tissue plasminogen activator (t-PA) greatly improved prognosis for CVA • aspirin (makes plts slippery fewer clots) • blood thinners
Sequelae of CVA • Aphasia: from damage to left side cerebrum where language centers are • Motor Aphasia: • damage to Broca’s area • loss of ability to speak • Sensory Aphasia: • loss of ability to understand written or spoken word
TIA • Transient Ischemic Attack • “mini-stroke” • due to temporary restriction of blood flow • symptoms last 5 – 50 minutes • “red flags” that warn impending & more serious CVAs
Alzheimer Disease (AD) • most common type of dementia • >10% population > age 65 • 4th leading cause of death in US • characterized by progressive loss of reasoning & ability to care for oneself • cause of most cases unknown but… • genetic factors • environmental or lifestyle factors • normal aging process