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Methodology of Human Risk Assesment

Methodology of Human Risk Assesment. Dr. Manfred Wentz Director, Hohenstein Institutes (USA) Head, Oeko-Tex Certification Body (USA) AAFA – Environmental Committee Meeting November 10, 2008 - Washington, D.C. Sustainability of Global Textile Market Triple Bottom Line (TBL) – Willard (2002).

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Methodology of Human Risk Assesment

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  1. Methodology of Human Risk Assesment Dr. Manfred Wentz Director, Hohenstein Institutes (USA) Head, Oeko-Tex Certification Body (USA) AAFA – Environmental Committee Meeting November 10, 2008 - Washington, D.C. M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  2. Sustainability of Global Textile MarketTriple Bottom Line (TBL) – Willard (2002) M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  3. Environmental Sustainability M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  4. Concept of Textile Ecology M. Wentz, Oeko-Tex (USA) - AAFA/RSL 4

  5. Human Ecology Challenges (EPA) Life stage Low Dose Acute Cumulative Improving human exposure assessment Applying novel biological data: Toxic genomic Human Health Risk Assessment Characterizing uncertainty (weight of evidence) Estimating risk from diverse exposure scenarios: M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  6. What is a “Poison” ?“Dose makes the Poison” “All things are poison, and nothing is without poison. It is the dose only that makes a thing not a poison.” Paracelsus (1494-1541) M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  7. Toxics - Basic Definitions M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  8. Risk - Basic Definitions M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  9. Exposure and Toxicity M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  10. Types of Toxic Effects on Humans M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  11. Risk Assessment and ManagementNational Research Council (1983, 1996) M. Wentz, Oeko-Tex (USA) - AAFA/RSL 11

  12. Typical Assays for Human Risk Assessment M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  13. General Risk Assessment Process M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  14. EPA- Design for the Environment (DfE)Voluntary Stakeholder Program M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  15. Chemical and Pesticides Results Measures (CAPRM) 145Environmental Indicators (EPA/OPPTS-FSU Project) • Human Health • Ecological Health • Chemical and Pesticides • Food Safety • Product Safety • Transboundary Movement • Product Steward ship • Pollution Prevention M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  16. CAPRM /EPA Hierarchy of Indicators M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  17. Complex Process of Regulatory DecisionsSource: EPA M. Wentz, Oeko-Tex (USA) - AAFA/RSL

  18. Factors Affecting Risk Perception“Perception is Reality” Increased Public Concern Decreased Public Concern M. Wentz, Oeko-Tex (USA) - AAFA/RSL 18

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