1 / 11

Tay-Sachs Disease Done by;; Shaquawn Marsalis && Shannon Robinson

Tay-Sachs Disease Done by;; Shaquawn Marsalis && Shannon Robinson. Where did Tay-Sachs come from && What is it?. The disease Tay-Sachs was named after Warren Tay [1843-1927] and Bernard Sachs[1858-1944]. Tay-Sachs is a fatal, yet recessive genetic disorder in children.

karif
Download Presentation

Tay-Sachs Disease Done by;; Shaquawn Marsalis && Shannon Robinson

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tay-Sachs DiseaseDone by;;Shaquawn Marsalis&&Shannon Robinson

  2. Where did Tay-Sachs come from && What is it? • The disease Tay-Sachs was named after Warren Tay [1843-1927] and Bernard Sachs[1858-1944]. • Tay-Sachs is a fatal, yet recessive genetic disorder in children. • Tay-Sachs causes progressive destructions of the central nervous system.

  3. What causes Tay-Sachs? • Tay-Sachs is caused by the absence of the vital enzyme called hexosaminidase. • Hexosaminidase is also known as Hex-A. • Ganglioside is also known as GM2. • Without Hex-A the fatty substance GM2 accumulates abnormally in cells, especially in the nerve cells of the brain.

  4. Mutation Plan • Mutations in the HEXA gene disrupt the activity of beta-hexosaminidase which prevents the enzyme from breaking down GM2. • This substance accumulates to toxic levels, which particularly damages the neurons in the brain and spinal cord.

  5. Population • Tay-Sachs occurs significantly high in persons of eastern European (Ashkenazi) Jewish descent. About one in every 27 Jews in the United States is a carrier of the Tay-Sachs' gene.

  6. What is body part is affected and what is the normal function? • Your brain and spinal cord is what is affected. • The normal function is when the space around your spinal cord and brain is covered with a fatty material.

  7. Symptoms • Seizures • Increased startle reaction • Decreased eye contact • Listlessness • Increasing irritability • Slow body growth with increasing head size • Delayed mental and social skills • The More Severe Symptoms • Feeding difficulties • Abnormal body tone • Loss of motor skills • Blindness • Deafness • Loss of intellectual skills

  8. Treatment • There is no Treatment • For tay-sachs

  9. Diagnosis • Apparent in the late 1st year of the babies life if he/she doesn’t start to respond and act like a maturing baby.

  10. References http://www.mayoclinic.org/tay-sachs-disease/symptoms.html http://ghr.nlm.nih.gov/condition=taysachsdisease http://www.mamashealth.com/tay.asp

  11. Thank You for Watching

More Related