Adrenoceptor Antagonists α-Adrenoceptor Antagonists
Non-selective Irreversible antagonist phenoxybenzamine , that binds covalently to receptor, long duration of action of 14-48 hours Reversible competitive antagonist phentolamine & tolazoline. Selective α 1 -adrenergic antagonists: prazosin, doxazocin & tamsulosin ( α 1A -blocker )
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