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SARS outbreak

SARS outbreak. SARS Outbreak. March 10 7 MDs and 4 nurses reported sick March 11 50 staff screened, 23 admitted, ward closed March 12 Clinical teaching suspended March 13 Index case identified March 17 Medical school moved back to campus . 156 patients 138 traceable to the index case

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SARS outbreak

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  1. SARS outbreak

  2. SARS Outbreak March 10 7 MDs and 4 nurses reported sick March 11 50 staff screened, 23 admitted, ward closed March 12 Clinical teaching suspended March 13 Index case identified March 17 Medical school moved back to campus

  3. 156 patients 138 traceable to the index case 20 doctors 34 nurses 15 allied health 16 medical students

  4. Immune hyperactive phase Pulmonary-destruction phase Viral replicative phase SARS: a triphasic disease Max. daily body temperature (oC) Days after onset of disease

  5. Treatment Protocol Broad spectrum antibiotics IV Ribavirin High dose steroids Convalescent serum Supportive care

  6. Response to Rx

  7. All patients in PWH • N=277 • Discharged: 147 (53%) • ICU admission: 51 (18.4%) • Died: 18 (6.5%) • Mortality : median age 76 (44-84) years

  8. Convalescent Plasma

  9. Convalescent Plasma vs more MP

  10. Outcome of patients who received CS before day 16 vs later date

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