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Supplementary Figure 1. a. Pyruvate + D -glyceraldehyde-3-phosphate. DXS. 1-deoxy- D -xylulose 5-phospate. DXR. 2 C -methyl- D -erythritol 4-phosphate. IspD. 4-diphosphocytidyl-2 C -methyl- D -erythritol. IspE. 4-diphosphocytidyl-2 C -methyl- D -erythritol 2-phosphate. IspF.
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Pyruvate + D-glyceraldehyde-3-phosphate DXS 1-deoxy-D-xylulose 5-phospate DXR 2C-methyl-D-erythritol 4-phosphate IspD 4-diphosphocytidyl-2C-methyl-D-erythritol IspE 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate IspF 2C-methyl-D-erythritol 2,4-cyclodiphosphate IspG 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate IspH Isopentenyl diphosphate {IPP} Dimethylallyl diphosphate {DMAPP} IDI Supplementary Figure 1 b c
Supplementary Figure 2 TRV TRV:DXS TRV:IspD TRV:IspH
Supplementary Figure 3 TRV TRV:IspE