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A New Vision for High Throughput Materials and Interfaces Research

A New Vision for High Throughput Materials and Interfaces Research. Dr. John Brennan. April 2, 2013. New Approaches to Materials Characterization. High Information Content Methods to Chart Biointerface Interactions. High end MS/MS for surface proteomics (stealth materials )

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A New Vision for High Throughput Materials and Interfaces Research

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  1. A New Vision for High Throughput Materials and Interfaces Research Dr. John Brennan April 2, 2013

  2. New Approaches to Materials Characterization High Information Content Methods to Chart Biointerface Interactions • High end MS/MS for surface proteomics (stealth materials) • ssNMR – high field for extremely detailed interaction information • Imaging XPS for surface characterization • NSOM / TIRF gives single molecule level details of nature of environments • Database to bring together all data for modelling and new insights 2

  3. Potential for Interfacial Materials High-Throughput production of multiple surface chemistries • Rapidly produce materials with polymer or small molecule coatings • Rapidly print biological reagents onto substrates High-Throughput characterization • Imaging XPS, MALDI, IR (quantity and distribution) • BIOACTIVITY SUITE (gels, immunoblots, protein binding) • Specifiv vs. non-specific binding 3

  4. Potential for Interfacial Materials 4

  5. Thank You Funding and Support Fred Capretta Cathy Bottos Leanne Brown Dawn White ElnaLuckham Danielle Covelli Dan Wallace Brandon Aubie Steve Kornic biointerfaces.mcmaster.ca

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