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Why do we care about pain?. One of the most common health problems that causes people to seek medical attentionPain is actually beneficial to long-term health and survival. What is pain?. ?An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described
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1. Health Psychology Chapter 9 – Pain and Pain Management
PY 470 Hudiburg
2. Why do we care about pain? One of the most common health problems that causes people to seek medical attention
Pain is actually beneficial to long-term health and survival
3. What is pain? “An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage” ISAP (1979)
Pain is what the person says hurts
Acute pain – shorter duration up to six months
Acute monophasic pain
Recurrent acute non-malignant pain
Chronic pain – longer duration > six months
Chronic malignant pain - progressive
Intractable-benign
Chronic pain associated with non-malignancy disease – identifiable pathology
Chronic non-malignant pain syndrome
Recurrent acute - migraine
Chronic and acute pain my have different causes – behavioral factors may be involved in acute pain
4. How do we experience pain? Specificity theory – Descrates
posits that there are specific sensory receptors for different types of sensations (i.e., pain, touch, pressure)
Pattern theory – Melzack & Wall (1982)
posits that pain results from the type of stimulation received by the nerve ending and the key determination of pain is the intensity of the stimulation
Both theories have limitations
pain can be experienced without tissue damage
tissue damage can occur without pain being felt
Phantom limb pain experience not accounted for by the theories – Fordyce (1988) study of amputees
Continuing to perform despite pain
5. Gate Control Theory Gate control theory –
Melzack & Wall (1965) - Figure 9.2, p. 320
severity of pain sensation determined by balance between excitatory and inhibitory inputs to T cells in spinal cord
C & A-delta nociceptor afferents give excitatory input to dorsal root ganglion of spinal cord– A-delta (myelinated) about 40 mph and C fibers (unmyelinated) about 3 mph, other sensory information travels at about 180 -240 mph
Substantia gelatinosa, large diameter A-beta non-nociceptor afferents give inhibitory input
Increased firing of non-nociceptor afferents causes presynaptic inhibition of T cells and the spinal gate from excitatory cells to the brain is closed. – Figure 9.2, p. 322
Physical agent modalities and physical activities believed to close the gate by activating the non-nociceptor afferents
The theory does not explain pain modulation descending from brain
6. Central Control Mechanisms of Pain Not well understood
Periaqueductral gray seems to be involved in pain – electrical stimulation can block the experience of pain – Figure 9.1, p. 320
Spinothalamic tract which carries the impulses up the spinal cord, through the brain stem to the thalamus
Cerebral cortex
sensory area of parietal lobe: localization and interpretation of pain - somatosensory cortex
limbic system: affective and autonomic response
temporal lobe: pain memory
8. Chemical processes involved in pain Substance P –
Figure 9.3, p. 323
Chemical mediator thought to be involved with transmission of pain.
Associated with inflammatory pain
It excites pain transmitting neurons when released
Its mechanism is not fully understood
Glutamate – release affects amount of pain experienced
Prostaglandins, bradykinin – released when tissue damaged
9. Chemical processes involved in pain Endorphins Pain perception modulated by these opiate like neurotransmitters
The endorphins bind to certain sites on the nervous system including peripheral nerves
They suppress pain transmission at the spinal cord level by inhibiting the release of the neurotransmitter gamma aminobutyric acid (GABA) in the periaqueductal gray matter (PAGM) and raphe nucleus of the brain
High concentration of opiate receptors in limbic area of brain explains the stress relief and euphoria associated with opiates
Limbic system involved with emotional component of pain
Neuromatrix – pain and amputated limits
10. How is pain measured? Physiological measures
EMG – muscle tension
Heart rate
Skin temperature
EEG and brain imaging
Behavioral pain measures
Physical symptoms
Clusters: guarding, bracing, rubbing, grimacing, and sighing
Symptoms can be misrepresented: report and unobtrusive observation differences – Kremer et al. (1981)
Self-report measures
11. McGill Pain Questionnaire – Figure 9.4, p. 327 in textbook has McGill-Melzack scale- sensations- feelings- intensity
12. Pain Rating Scales Visual Analog Scale(VAS)
Graphic Rating Scale(GRS)
Simple Descriptor Scale(SDS)
Numerical Rating Scale(NRS)
Faces Rating Scale(FRS)
13. Pain Rating Scales
14. Pain Cycle This slide depicts the possible cycle of pain for those with ineffectively resolved or managed pain.
Source: Gill , T. 1997, Patients with Pain and Drug Use Problems, GP Drug and Alcohol Supplement No. 4, Central Coast Area Health Service, p. 3.
This slide depicts the possible cycle of pain for those with ineffectively resolved or managed pain.
Source: Gill , T. 1997, Patients with Pain and Drug Use Problems, GP Drug and Alcohol Supplement No. 4, Central Coast Area Health Service, p. 3.
15. How do psychological factors influence the experience of pain? Learning
modeling
secondary gain / reinforcement – parents and children’s pain
financial
culturally learned
16. How do psychological factors influence the experience of pain? Cognition
relative to what?
causes of pain (i.e., debilitating condition vs. minor (and fixable) problem
anticipation of pain is often worse than pain itself
expectations of their ability to cope
Box 9.1, p. 332, Women’s belief about rates of PMS and PMS symptoms – Figure 9.6, p. 333
Coping strategies – Table 9.2, p. 335
17. How do psychological factors influence the experience of pain? Personality
anxiety and depressive disorders are associated with chronic pain
extroversion is associated with higher pain thresholds
internal locus of control is associated with believe of better coping – Table 9.3, p. 335
bulk of evidence suggests that chronic pain LEADS to depression, and not the reverse
18. How do psychological factors influence the experience of pain? Stress
pain is influenced by stress such as family/marital problems, work pressures, major life events, etc.
stress leads people to engage in behaviors (i.e., grinding teeth, tensing muscles), which in turn lead to pain
Figure 9.7, p. 337 – Biological, psychological, and social factors influencing experience of pain
19. What are some physical methods of controlling pain
20. What are some physical methods of controlling pain: Medications Opioid analgesics: substance P release into dorsal horn regulated by endogenous endorphins and exogenous opioids. Inhibit substance P release
opioid=any antagonist with morphine-like activity
opiate=drug from the poppy i.e. morphine and codeine
21. What are some physical methods of controlling pain: Medications Morphine
Acts on mu receptors, produces intense analgesia and indifference to pain
alters central processing of pain (thalamus, limbic system and cerebral cortex)
receptors present in brain and spinal cord: periaqueductal grey (PAG), caudal and geniculate nucleus, thalamus and spinal cord
OxyContin – “hillbilly heroin” – issues of control – Box 9.2, p. 338
Synthetics opiates
Local anesthetics
22. What are some physical methods of controlling pain: Medications NSAID’s - Non-steroidal anti-inflammatory drugs
Aspirin, ibuprofen, naproxen, phenylbutazone, ketoprofen, diclofenac
may cause kidney damage, bone marrow suppression, rashes, decrease renal blood flow in dehydrated pts
Acetaminophen (Tylenol)
has analgesic and antipyretic (fever reducing) effect, but no anti-inflammatory effect
prolonged use can cause liver damage
23. What are some physical methods of controlling pain: Surgery Surgery:
115,000 laminectomies and 34,000 lumbar spine operations in U.S.
Rotator cuff injury and repair
24. What are some physical methods of controlling pain? Physical stimulation Physical stimulation
Counterirritation – irritating body tissue to ease pain
Transcutaneous electrical nerve stimulation (TENS)
Acupuncture - Photo 9.4, p. 342
Several techniques but usually associated with Chinese
long, thin needles inserted into body – based on body’s energy flow in 14 distinct channels - Cost - $40, usually $80 -
Massage therapy
There are over 200 massage techniques
Acupressure, Aromatherapy, Hot Stone Massage, Reflexology, Swedish Massage (traditional massage)
Chiropractic therapy – issue of use and effectiveness
Issues: short-term effects
In most cases, there was little difference between these and placebo. Interestingly subjective reports state the opposite.
25. What are some physical methods of controlling pain? Physical therapy – increase flexibility and muscles conditioning
Exercise
Regular exercise has lasting effects – Frost et al. (1998) – to reduce back pain, two years after participation reduced disability
Combined with other treatments to increase effectiveness – Turner et al. (1990) use of behavioral therapy and exercise
26. Is this pain? Will this be painful?
27. What are some of the psychological methods of controlling pain? Hypnosis
Biofeedback
Relaxation and distraction
Cognitive - Behavior therapy
Behavioral Medicine – Society of Behavioral Medicine - pain
28. What are some of the psychological methods of controlling pain? Hypnosis Trancelike state
Mesmer made famous
Multiple Definitions
altered state of consciousness
trait of hypnotizability
Hypnotized people:
will perform minor feats,
won’t hurt self, others
29. Hypnosis Process Relaxation
Told it will ? pain (suggestion)
Induction = being placed under hypnosis (distraction)
Instructed to think of pain differently (reinterpretation)
30. Hypnosis Outcomes Surgery, childbirth, dental procedures, burns, headaches
Unclear: block pain OR alter reports
NOT better for low suggestible points
Better for high suggestible points
Figure 9.8, p.345 – burn patients – Patterson et al. (1992)
Figure 9.9, p.346 – susceptible levels and pain reduction – Hilgard (1975)
31. What are some of the psychological methods of controlling pain? Biofeedback Definition = providing information on typically involuntary bodily process to learn to control it
e.g., bp, hr, skin temp
Electromyograph (EMG) = electrical discharge in muscle fibers
Thermister = skin temperature
Audio/visual signal
Trial/error- pt changes thoughts, behaviors
32. Biofeedback Outcomes Joint pain, migraine headache, hypertension
Expensive technology & trained personnel
Relaxation & hypnosis cheaper & easier
NOT better for stress
Better for migraines
Figure 9.10, p. 347 – Gauthier et al. (1994) for headaches
33. Behavioral/Cognitive Approaches Distraction
Other activity (e.g., pledge of allegiance) – Box 9.3, p. 351 – movie before vaccinations – Cohen et al. (1999)
Reinterpretation (e.g., secret agent)
Better for short-term, low-level pain
Music and pain reduction – Figure 9.11, p. 349 – Anderson et al. (1991)
Relaxation
Progressive technique
Autogenic technique – use of self instructions of warmth and heaviness
Treatment of recurrent headache – Holroyd & Penzien (1994)
34. Behavioral/Cognitive Approaches Guided Imagery – Table 9.5, p. 348 TRIP
Systematic desensitization
Reframing
Meditation
Stress management techniques – not as effective as other techniques
Thinking about the pain and expectations – Box 9.5, p. 354-355 – Bandura et al. (1987) – Figure 9.12, p. 355 – an increase in endorphines with cognitive technique
35. Can placebos decrease pain?- Figure 9.13, p. 359 – Gracely et al. (1985)
36. How do placebos influence pain? Patient’s expectation about the effects of the treatment
Ariely (2008) study of differential effectives of placebo based on perceived cost ($.10 v. $2.50)
http://www.npr.org/templates/story/story.php?storyId=87938032
Classical conditioning
Patient’s may change behaviors
Physiological changes which inhibit the experience of pain
37. How do placebos influence pain? Research
Expectation effects
Interactions with health care providers – Talbot (2000) – 70 -25 % effective based on attitude of the practitioner toward the placebo
Nocebo effect – negative effects of the placebo condition
38. Lingering issues Does the duration of pain matter?
Time limiting aspects of pain may affect pain experiences
Can placebo surgeries be effective?
Suggested research – Beecher (1959), Moseley et al. (2002) – no difference in pain levels but actual surgery patient more functional – patients’ belief is important