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Please complete the biology class assignments provided and communicate any questions with the teacher during a temporary absence. Ensure to use the links given for the quizizz and readings.
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Thursday, January 3, 2019I will not be in school (at least not on a regular basis) for 2-6 weeks. The assignments that you are given are not optional. It is imperative that you complete the assignments (quizizz, readings, PPT, notetakers, hwk, etc.). It is equally important that you communicate with me when you have a question about a lesson. Mrs Turner has my number. You can call me from the classroom phone or from your cell during class (if you have verizon, you can make calls from my classroom – if the weather is cloudy, sit at the lab table in front of the big window to make the call).
Thursday, January 3, 2019If you did not complete the monomer/polymer quizizz yesterday, do that now. https://quizizz.com/admin/quiz/5c23c9a7d74608001af706d2/mausome-monomers-and-polymers If you did complete that quizizz, continue to the next slide.
Thursday, January 3, 2019For a review of yesterday’s lesson, complete the quizizz that accompanied the nucleic acid monomer/nucleotide PPT and notetaker. https://quizizz.com/admin/quiz/5c23dd9cd74608001af74431/mausome-dna-and-nucleotides If you did not yet read yesterday’s reading assignment (page 48), do so now.
Thursday, January 3, 2019 Then begin to follow this PPT and complete your notetaker (section 2). When you have completed that, complete the quizizz review that accompanies it. https://quizizz.com/admin/quiz/5c23f5e6d74608001af78fb9/mausome-dna-structure Keep in mind, you are not completing the notetaker for the simple task of completing the notetaker, you should be trying to understand the information embedded in the PPT.
Section 3C – Macromolecules (Nucleic Acids and Molecular Genetics) Part 2: DNA – Structure
Part 2: DNA – Structure Solving the structure of DNA involved many experiments, over many years
Part 2: DNA – Structure Objectives: Identify key players/contributions in DNA research Identify parts of a nucleotide, structure of DNA Describe complementary base-pairing of DNA Explain the organization of DNA in chromosomes
Part 2: DNA – Structure DNA Structure I. DNA is a nucleic acid called deoxyribonucleic acid
Part 2: DNA – Structure DNA Structure A. DNA is made of monomers called nucleotides
Label the nucleotide accordingly Nitrogen base Phosphate group Deoxyribose (Pentose sugar)
Part 2: DNA – Structure DNA Structure 1. DNA nucleotides contain one of four nitrogen containing bases
Part 2: DNA – Structure DNA Structure a. Cytosine b. Thymine c. Guanine d. Adenine
Part 2: DNA – Structure DNA Structure -Pyrimidines (thymine & cytosine) have 1 ring
Part 2: DNA – Structure DNA Structure *mnemonic* Pyrimidines (thymine & cytosine) have 1 ring Small structure, big name
Part 2: DNA – Structure DNA Structure Purines (A and G) are two rings
Part 2: DNA – Structure DNA Structure Purines (A and G) are two rings *mnemonic* “Purine” has 2 syllables (2 rings) All Good things are PURE
Part 2: DNA – Structure DNA Structure
Part 2: DNA – Structure DNA Structure 2. Sequence of the basesprovide blueprintfor the organism
Part 2: DNA – Structure DNA Structure C. (1950) Erwin Chargaff
Part 2: DNA – Structure DNA Structure (1950) Erwin Chargaff
Part 2: DNA – Structure DNA Structure
Part 2: DNA – Structure DNA Structure What did Chargaff learn from his study? BPR
Part 2: DNA – Structure DNA Structure 1. Chargaff’s data revealed that nucleotide ratios are conserved (consistent) across all species
Part 2: DNA – Structure DNA Structure Meaning: The amount of A = T and C = G … always!
Part 2: DNA – Structure DNA Structure (1951) Rosalind Franklin
Part 2: DNA – Structure DNA Structure 1. Used X-ray diffraction to take pictures of DNA
Part 2: DNA – Structure DNA Structure Produced: photo 51 which indicated DNA was shaped like a double helix
Part 2: DNA – Structure DNA Structure E. (1953) James Watson and Francis Crick
Part 2: DNA – Structure DNA Structure 1. Used the data of others to build a model of DNA
Part 2: DNA – Structure DNA Structure a. Two outside strandsof alternating sugarsand phosphates heldtogether bycovalent bonds(rails of a ladder)
Part 2: DNA – Structure DNA Structure b. Nitrogen bases “stack”on the inside(steps of a ladder)
i. The complementary base-pairs are bonded thusly: G formshydrogen bonds to C andA forms H bonds to T Part 2: DNA – Structure DNA Structure Sugar Sugar Sugar
You do: How many H-bonds connect A-T? ____ Highlight them. How many H-bonds connect G-C? ____ Part 2: DNA – Structure DNA Structure Sugar Sugar Sugar
What type of line is used to represent H bonds? _______________ Remember: nucleotides are held together by covalent bonds. Are H bonds stronger or weaker than covalent bonds? _________________ Part 2: DNA – Structure DNA Structure Sugar Sugar Sugar
Examine Part 2: DNA – Structure DNA Structure Sugar Sugar Sugar Thymine(T) Guanine (G) Adenine (A) Cytosine (C)
Part 2: DNA – Structure DNA Structure
Part 2: DNA – Structure DNA Structure c. The orientation of the twoDNA strands is calledanti-parallel
Part 2: DNA – Structure DNA Structure You do: Draw a single arrow over the sugars on the left and another over the sugars on the right in order to represent the anti-parallel nature of the DNA molecule. Circle a nucleotide on the left handrail and circle one on the right handrail.
Part 2: DNA – Structure DNA Structure d. Watson and Crickwon the 1953 Nobel Prize for their work on DNA structure
Part 2: DNA – Structure DNA Organization To prevent tangling of DNA in eukaryotes:
Part 2: DNA – Structure DNA Organization (1) DNA is wrapped around histone proteins
Part 2: DNA – Structure DNA Organization (2) DNA coils around histones, forming nucleosomes
Part 2: DNA – Structure DNA Organization (3) Nucleosomes coil into chromosomes DNA supercoil
Part 2: DNA – Structure Activity – DNA Models When Watson and Crick solved the structure of DNA, it opened up the entire field of molecular biology.
Part 2: DNA – Structure Complete this quizizzand the reading in your text book. https://quizizz.com/admin/quiz/5c23f5e6d74608001af78fb9/mausome-dna-structure Read pgs 344-348