1 / 15

Staging of Chronic Kidney Disease

Staging of Chronic Kidney Disease. I.N. Slotki, MD Division of Adult Nephrology Shaare Zedek Medical Center. Reasons for diagnosing CKD. Common- >10% of population (US) Largely unidentified or ignored Rx available to prevent or delay progression Probably largest single risk factor for CVD

keena
Download Presentation

Staging of Chronic Kidney Disease

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Staging of Chronic Kidney Disease I.N. Slotki, MD Division of Adult Nephrology Shaare Zedek Medical Center

  2. Reasons for diagnosing CKD • Common- >10% of population (US) • Largely unidentified or ignored • Rx available to prevent or delay progression • Probably largest single risk factor for CVD • >50% of CKD patients die from CVD • Rx of ESRD is expensive • Numbers of patients reaching ESRD are steadily increasing

  3. Global maintenance dialysis population 1990-2010 2095 Thousands of patients 1065 426 Lysaght JASN 2002

  4. People at increased risk of CKD • Normal GFR + markers of kidney damage • Risk factors for adverse outcomes of CKD

  5. Risk factors for CKD and its outcomes Susceptibility Initiation Progression End-stage

  6. Risk factors for CKD and its outcomes • Factors that susceptibility to kidney damage • Age • Family history • Kidney mass • Low birthweight • Low income/education Susceptibility

  7. Risk factors for CKD and its outcomes • Factors that directly initiate kidney damage • Diabetes • HTN • Hereditary diseases • Autoimmune diseases • Systemic infections • UTIs • Lower tract obstruction • Drug toxicity Initiation

  8. Risk factors for CKD and its outcomes • Factors that cause worsening kidney damage & faster decline in kidney function • proteinuria • BP • Poor glycemic control in diabetics • Smoking • ?Hyperlipidemia Progression

  9. Risk factors for CKD and its outcomes • Factors that morbidity & mortality in kidney failure • Anemia • albumin • dialysis dose • Temporary vascular access End-stage • Late nephrology referral

  10. Markers of kidney damage • Kidney damage for 3 months • Proteinuria (albumin/creatinine ratio >30 mg/g in spot urine) • Abnormal sediment • Abnormal blood or urine chemistry • Abnormal imaging studies • Kidney function for 3 months

  11. Reasons for staging renal disease • Confusion in terminology • Chronic renal • failure • insufficiency • disease • Advanced renal failure • ESRD • Pre-dialysis Mild/Moderate/Severe

  12. Stages of CKD

  13. Estmating GFR הנוסחה ע"ש Cockroft & Gault (140-age) x Weight x 0.85 בנשים Plasma creatinine x 72

  14. Optimal Care of Chronic Kidney Disease

More Related