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Research Needs to Support Food-based Dietary Guidance in an Era of Over-Nutrition Tetrapartite Meeting, June 2008. Allison A. Yates, PhD, RD Director Beltsville Human Nutrition Research Center USDA/ARS Beltsville, MD. Today’s Discussion.
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Research Needs to Support Food-based Dietary Guidance in an Era of Over-Nutrition Tetrapartite Meeting, June 2008 Allison A. Yates, PhD, RDDirectorBeltsville Human Nutrition Research Center USDA/ARS Beltsville, MD
Today’s Discussion • Overview of food and nutrition research at ARS • Human Nutrition Action Plan 2009-2013 • Research issues on the agenda
Human Nutrition Research -- $85 M • Six human nutrition research centers • Houston TX & Baylor University: children • Boston MA & Tufts University: aging • Little Rock AR & Arkansas Children’s Hosp.: early nutrition (para-conceptional) • Grand Forks ND @ Univ. No. Dakota: rural concerns • Davis CA @ Univ. Calif at Davis: chronic disease • Beltsville MD @ BARC: adults; nutrition monitoring • Other specific projects @ ARS locations
ARS Human Nutrition Research Program Customers • Other governmental food and nutrition action agencies • USDA’s Food and Nutrition Service (FNS) • Food Stamp Program; WIC Food Program; MyPyramid Food Guide • USDA’s Economic Research Service (ERS) • National Institutes of Health • Methods to estimate food intake and dietary patterns when correlating diet and risk of disease, • Nutrient Database; Dietary Supplement Database • Polyphenol studies related to chronic disease risk factor reduction • U.S. Food and Drug Administration (FDA): scientific basis of nutrition regulations • Dietary Guidelines for Americans – Joint USDA/DHHS • Commodity trade associations, food processors • Advocacy groups improving the health of vulnerable groups
ARS Human Nutrition Mission To improve the nutrition and health of the American people by enhancing the quality of the American diet and improving related health behaviors through research From the 2009-2013 Action Plan: National Program 107 — Human Nutrition
2009-2013 Human Nutrition Action Plan Four Components • Nutrition Monitoring and the Food Supply • Scientific Basis for Dietary Guidance for Health Promotion and Disease Prevention • Prevention of Obesity and Related Diseases • Life Stage Nutrition and Metabolism
Steps to Develop Action Plan • Led by National Program Staff • Review of past 5 years of overall research by external review group • Workshop with stakeholders (customers), laboratory scientists, and invited academics • Purpose: identify needed research areas for future investment • Action plan developed with overall themes • Put out for comment prior to finalization
Use of Action Plan • National program staff develop objectives for 5 years for scientists given their expertise and priority areas in plan • Scientists develop outline of future research projects--- approved by Center directors, Area directors, finally National Program staff • Scientists submit full proposal for 5-year period addressing objectives and describing gaps to be filled, research plans, collaborations identified • Plans evaluated by blinded external reviewer panels to determine if proposed research is sound
Major Issues in Nutrition • Evolution from public health directives for nutrition guidance to individualized personal nutrition recommendations • New methods to detect specific risk factors for chronic diseases • Emerging role of immune response/inflammatory disease as intermediary in expression of chronic disease (CVD, diabetes, cancer, obesity) • Investigation of the health-promoting properties of foods---when are other food components considered nutrients?
Dietary Guidelines Versus RDAsConceptually • Dietary Guidelines: Qualitative advice to the public about diet and chronic disease prevention • Recommended Dietary Allowances (RDAs): Quantitative advice to professionals about amounts of nutrients or food components found to be of benefit
Major Issues in Nutrition • Obesity Causation and Prevention • Physiological contributors • Social context • Environmental contributors
Obesity Research at Beltsville Human Nutrition Research Center--- Stemming the Epidemic Obesity Trends* in the U.S.: % of Adults with BMI 30 by State Weight maintenance = energy intake – energy expenditure, or does it? What causes insulin resistance? How much is heredity, and how much is the environment? 1995 2000 Beltsville has the only USDA human studies facility with three live-in calorimeters to evaluate energy metabolism and the effect of various foods & exercise on body weight and energy regulation No Data < 10% 10-14% 15-19% 20-24% 25-29% 30% Does dietary fiber increase satiety, helping in weight management? BHNRC scientists found that barley fiber increased satiety in women 2005 Can dairy products assist in weight loss? BHNRC scientists find that whey protein maintains muscle mass and may decrease body fat When will the U.S. turn completely red? 2010? (* or about 30 lbs overweight for 5’4” person; Source, BRFSS, CDC )