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2004 Accomplishments and 2005 Objectives

9 th Annual PulseNet Update Meeting, Seattle, WA. 2004 Accomplishments and 2005 Objectives. Bala Swaminathan, Ph.D. Centers for Disease Control and Prevention. PulseNet Activity, 1996-2004. *. 2004 PFGE Pattern Submissions.

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2004 Accomplishments and 2005 Objectives

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  1. 9th Annual PulseNet Update Meeting, Seattle, WA 2004 Accomplishments and 2005 Objectives Bala Swaminathan, Ph.D. Centers for Disease Control and Prevention

  2. PulseNet Activity, 1996-2004 *

  3. 2004 PFGE Pattern Submissions • 38,682 PFGE patterns submitted to PulseNet databases in 2004, an increase of 37% over 2003 submissions • Increases in the 4 major pathogens • E. coli 37% • Salmonella 25% • Listeria 41% • Shigella 17% • 18,729 of 38,682 (48.4%) of submissions in 2004 were electronic submissions to the databases (This is a PART measure for CDC thatOMB evaluates. We exceeded the goal for 2004) • 27% increase over electronic submissions in 2003

  4. Clusters investigated by the PulseNet Task Force at CDC

  5. Four most common serotypes in the PulseNet USA Salmonella database

  6. Sources of the isolates in the PulseNet USA Salmonella database Environmental 1% Unknown 1% Animal 2% Food 2% Human 94%

  7. Web Service Tool for automated cluster detection • Daily cluster finding • Search for pattern numbers in PulseNet database by isolate ID • Frequency and geographic information on specific patterns • Graphical representation of data

  8. PulseNet International

  9. Why should we go international with PulseNet? • We live in a global community • Foods produced in one part of the world are consumed in another part of the world, 100’s to 1000’s of miles away • Diseases transmitted through foods should be addressed as a global problem • Need an effective global early warning system • Global networking and communication will allow us to utilize scarce public health resources effectively • Leverage the network to respond to other emerging infectious diseases or acts of bioterrorism

  10. Infrastructure is being set up • Have a robust communication network • PulseNet server being set up – subsequent linkage to PulseNet USA server planned • Close to agreement on MOU and TOR • Continue real-time exchange of data • Model for other inter-country networks

  11. PulseNet Europe • September 2004 – EU funding kicked in • Database infrastructure has been set up • Working on setting up various databases • Dr. Susanna Lukinma has replaced Dr. Peter Gerner-Smidt as the coordinator of PulseNet Europe.

  12. Progress documented in a special edition of PulseNet News • 2nd PulseNet Workshop conducted in Hong Kong in March 2005 • Vibrio cholerae standardized protocol evaluation – Hong Kong, Japan, Bangladesh working with PulseNet USA • NIID, Japan has been successful in obtaining funding to support the network and/or countries that need assistance • Strategic planning meeting scheduled for 4th quarter of 2005

  13. E. coli O157:H7 outbreak in Japan

  14. PulseNet’s Role in Outbreak Investigation • 2/2004: 3 cases identified by OCHC, Japan • Family purchased frozen ground beef patties from U.S. Military Commissary • PulseNet Japan performs PFGE using PulseNet protocol • PulseNet Japan sends query to PulseNet USA re: PFGE pattern • Pattern is not in PulseNet USA database

  15. PulseNet’s Role in Outbreak Investigation • PulseNet USA posts Japan pattern on WebBoard • CA state public health laboratory reports matches • Epidemiologic investigations begins • Additional cases identified in Idaho, Oregon and Washington • Trace back identifies specific lot produced by U.S. company on August 11, 2003 • 90,000 lb product recalled

  16. International Outbreak of Shigellosis, 2004

  17. PulseNet WebBoard Posting

  18. Shigellosis associated with meals served on Airline N • 9/3/04: PulseNet WebBoard posting by MN PHL • HI, MI, WA, UT, HOU, SDC, LAC, MA, and NJ respond to posting identifying matches • OH child hospitalized after return from HI via MN • 12 confirmed S. sonnei infections in Japan • PulseNet USA and PulseNet Japan compare patterns - indistinguishable

  19. Special PulseNet Issue Planned for March 2006 This new peer-reviewed, international journal publishes original papers and short communications on research and diseases caused by foodborne pathogens. Topics include emerging pathogens; emergence of drug resistance; methods and technology for rapid and accurate detection; strategies to destroy or control foodborne pathogens in food production and processing; and development of novel strategies for the prevention and control of plant and animal diseases that impact food safety. The Journal will include timely reviews and special reports on topics such as agroterrorism and the safety of organically grown and genetically modified foods.

  20. http://www.cdc.gov/pulsenet/index.htm

  21. Peter Gerner-Smidt, M.D., Ph.D. Kelley Hise Susan Hunter Desmond Jennings Molly Joyner Jennifer Kincaid Eija Trees Acknowledgements

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