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Portable High-Throughput Integrated Laboratory Identification System (PHILIS)

Portable High-Throughput Integrated Laboratory Identification System (PHILIS). Building Environmental Analytical Capability for Chemical Warfare Agents in Support of EPA’s Emergency Response Missions. Larry Kaelin National Decontamination Team US EPA Special Teams. PHILIS 1.

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Portable High-Throughput Integrated Laboratory Identification System (PHILIS)

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  1. Portable High-Throughput Integrated Laboratory Identification System (PHILIS) • Building Environmental Analytical Capability for Chemical Warfare Agents in Support of EPA’s Emergency Response Missions Larry Kaelin National Decontamination Team US EPA Special Teams Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  2. PHILIS 1 • 2004 - Originally, DHS-led initiative to produce a high-throughput screening system (original goal: 1000 samples/24 hrs) designed to identify and quantify Toxic Industrial Chemicals (TICs) and CWAs above permissible exposure limits (PEL) • Field Testing of 3 Prototype Designs completed July 2005 • All vendors failed field test in both number of samples and accurate identification of compounds • EPA expressed concerns that we did not wish to sacrifice quality for quantity • Department of Homeland Security (DHS) and EPA signed MOU for transfer residual PHILIS-1 equipment, and the development of new PHILIS 2 system • PHILIS 1 assets used to construct PHILIS 2 prototype mobile laboratories – PHILIS 2 completed and delivered to EPA’s National Decontamination Team (NDT) on April 2008 Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  3. Migrate PHILIS 1 to PHILIS 2 • The best aspects of the three PHILIS 1 systems were used to construct the new PHILIS 2 prototype (PHILBERT) • GC/MS w/FPD • Pressurized solvent extraction sample prep (PSE) • LC/MS-MS added • LIMS • The remaining PHILIS 1 assets were used as a starting point to construct new PHILBERT systems (pending in NJ and CO) • 10 – GC/MS systems (NJ) • 1 – LC/MS-MS added (NJ) • 2 - P & T systems added (NJ) • 3 – TOF GC/MS systems (CO) • SPE sample prep (CO) Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  4. PHILIS 1 - NJ • PHILIS 1 vehicles arrived in Edison, NJ in July 2007. Currently running under temporary shore power and shelter. • OEM will be responsible for operation and maintenance of PHILIS units, Region 2 providing warehouse/office space. • Renovations to warehouse to begin November 2008 • Currently capable of only analyzing TICs (method 8260/8270) • Edison unit includes 10 GC/MS instruments and a sample prep trailer. Two P & T, LC/MS-MS recently (October 2008) added. • A Sample Log-in Area (SLA) trailer needed • NDT will work with ERT and Region 2 emergency response program and laboratory on initial set up of lab. Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  5. NJ PHILIS Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  6. NJ PHILIS – 1 of 2 Lab Trucks Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  7. PHILIS Status - NJ • Have – Modified PHILIS 1 Systems • 2 – 24’ bed lab trucks (APL01-VOCs, APL02-SVOCs) • 1 – 24’ bed 5th wheel trailer w/Ford 550 for sample prep (SPA) • 1 – 12’ bed refrigerated box truck • 10 – GC/MS systems • 2 – P&T systems for VOCs • 1 – LC/MS-MS system (not in PHILIS, in Region 2 fixed laboratory) • Need - Permanent shore power and shelter solution • Support offices, storage, meeting/training rooms • Automated sample prep for SVOCs • HVAC renovations as per H&S requirements (if required) • Link in with Region 2 and EPA’s Lab Response Corps • SLA trailer w/UDA CWA standards secure room • LIMS upgrade Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  8. PHILIS 1 – CO • Denver PHILIS unit includes sample prep trailer and mobile laboratory bus with 3 time of flight (TOF) GC/MS systems. • OEM will be responsible for operation and maintenance of PHILIS unit. • Warehouse lease procurement currently underway • Projected move date to CO warehouse January 2009, linking with NCERT for shared warehouse/office space • Currently capable of only analyzing TICs • TOFs have potential to accelerate analysis time. Rapid TOF methods currently being developed and validated by NHSRC and NEIC Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  9. CO PHILIS Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  10. Time of Flight (TOF) GC/MSCO PHILIS Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  11. PHILIS Status - CO • Have – Modified PHILIS 1 System • 1 – 45’ mobile lab RV (PAL) • 1 – 53’ sample prep trailer (SPA) • 3 – TOF GC/MS systems w/rapid GC • 3 – SPE systems for SVOCs • Need - Permanent shore power and shelter solution • Complete lease transactions on warehouse lease • Support offices, storage area, meeting/training rooms • HVAC renovations as per H&S requirements (if required) • Link in with NCERT/NEIC for TOF methodologies • SLA trailer w/UDA CWA standards secure room • VOCs sample prep system (P&T systems) • Upgrade of SVOCs sample prep system (PSE systems) • LIMS upgrade Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  12. PHILIS 2 (PHILBERT) - KY • Mobile laboratory consortium of 3 vehicles • Analytical Trailer with 6 GC/MS systems and one LC/MS/MS system • Sample Preparation Trailer for prep. operations of soil, water, air, and wipe samples. • Sample Log-In and Standards (ultra-dilute CWAs) Storage trailer • Anticipated Capacity of 100 – 200 Toxic Industrial Chemical or Chemical Warfare Agent samples per 24 hr. period • Will analyze CWAs and their breakdown products using SW 846 methodologies found in Standardized Analytical Methods (SAM). • Delivered April 2008, awaiting renovations to current building for shore power and warehouse/office space. • Proposed location for CWA training and certification for EPA’s Laboratory Response Corps • Prototype for EPA’s future PHILIS systems Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  13. PHILBERT – KYSPA and PAL Trailers Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  14. PHILBERT – KYSLA Trailer (UD CWA Secure Room) Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  15. PHILBERT - KYLC/MS-MS System Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  16. PHILBERT Status - KY • Have – One Complete PHILIS 2 system in KY • 1 – 53’ lab trailer (PAL) • 1 – 53’ sample prep trailer (SPA) • 1 - 24’ bed 5th wheel trailer w/Ford 550 for sample log-in (SLA) • 6 - GC/MS w/FPD • 1 - LC/MS-MS • 3 - PSE automated sample prep for SVOCs • 2 - P & T systems for VOCs • Wireless LIMS • Need – Permanent shore power and shelter solution • Support offices, storage, meeting/training rooms • HVAC renovations as per H&S requirements (if required) • Link in with Region 5/NHSRC LC/MS-MS methodology R&D Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  17. PHILIS’ Mission • Fill perceived EPA’s gaps in the capability and capacity to analyze CWA contaminated environmental samples on-site • Provide timely analytical data during the Consequence Management Phase of the incident • Lower overall remediation costs • Lower analytical costs/ turn-around time for data • Allow more timely, on-site decisions during the characterization and remediation (decon) phases of the incident response • Provide reliable data on known QA/QC integrity for the “decision makers” during the final clearance and recovery phases of the incident • Reduce time to recovery • Validate SAM (through the ERLN) CWA analytical methods Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  18. How ?? • Provide high quality analytical data on-site, using validated methods • Automated and rapid sample prep • Rapid GC/MS, TOF-GC/MS and LC/MS-MS methods • MDLs at or below Risk-based clearance levels • Automated Laboratory Information System (LIMS) to track sample flow and produce field data of known QA/QC integrity Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  19. Next Steps • Short Term: Inventory, Set up, Power, Shelter and Storage • Convert remaining PHILIS 1 assets to PHILIS 2 • Set up for VOCs/SVOCs methods (8260/8270) • NELAC certification • Long Term: Develop a strategic plan and timeline to address: - Routine and emergency response use - Resources including staffing - Training • Long Range Goal: provide mobile laboratory platforms for the rapid, reliable on-site analysis of TICs and CWAs • ERLN certification for CWA UDA standards Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  20. PHILIS’ Mission in NJ • Integrate with Region 2 and ERT emergency response and laboratory programs • In fixed mode – provide surge capacity for routine analysis • In mobile mode – provide on-site analysis at Superfund sites • Platform for EPA’s Laboratory Response Corps training • Methods development and validation for SAM methods • Integration of PHILIS 2 into ERLN and UDA CWA programs • Dual Use of PHILIS systems • Prepare for and respond to CWA and TIC/TIMs incidents Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

  21. Questions • NDT Director: Steve Hawthorn • PHILIS Operations Manager: Larry Kaelin, NDT • CWA Methods and Validation: Terry Smith, OEM Kaelin.lawrence@epa.gov 732-452-6454 Building Environmental Laboratory Capability in Support of Emergency Response - The eLRN

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