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Mr. Wraga ASACS Counselor. RHS Health Classes discussion and support ppt 2014. Weed Brain-Impact on Hippocampus. How many hits to slow growth? 3 hits/week and HC stopped growing Catch up 6 mos to start growing again 2 yrs for every 1 yr of using Only up to age 25
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Mr. WragaASACS Counselor RHS Health Classes discussion and support ppt 2014
Weed Brain-Impact on Hippocampus • How many hits to slow growth? • 3 hits/week and HC stopped growing • Catch up • 6 mos to start growing again • 2 yrs for every 1 yr of using • Only up to age 25 • What’s funny about Cheech & Chong (Beevis & Butthead)? • Slowed speech; cadence • Monotone
cont • Other ways to help HC grow: • Sleep • Get off your butt • Lay off the stupid stuff • Example: Dementia home • 50 yr old man, weed since teen, lots of beads and electricity can’t get to where it wants to go • Can’t remember: Why he lives there, where he should go to the bathroom, what happened 10 min ago…
Impact! • Bat to head: What to watch for: • Nausea, lethargy, unconscious, seizures, headache, death (brain swelling), speech, eyes, disorientation, poor memory • Hangover • Black-out, headache, shaking (seizure), light sensitivity, …. • Both cases HC doesn’t grow for 6 months
Mice addicts • Adol mice given cocaine • End of HC swollen, not growing • No growth for 6 mos • FMRI showed same • Alpha Mouse has long HC • Can regulate mood • Learn new things
What is addiction? Addiction is a condition that results when a person ingests a substance (alcohol, cocaine, nicotine) or engages in an activity (gambling) that can be pleasurable but the continued use of which becomes compulsive and interferes with ordinary life responsibilities, such as work or relationships, even health. Users may not be aware that their behavior is out of control and causing problems for themselves and others.
Experimentation • The first stage, experimentation, is the voluntary use of alcohol or other drugs. Many times it involves teens going to a party and drinking or popping pills in order to fit in. Sometimes, the person experimenting is trying to forget about or escape from an issue. An older person may start drinking to cope with depression after losing a job. Experimentation may even include a teenager taking their mom’s prescription painkillers to cope with an injury from a sports activity. At the time the substance seems to solve the problem. The person takes more, and moves from experimentation to regular use, the next stage. Curiosity.
Risky Use • Behavior has changed noticeably and/or suddenly • Consequences begin to build • May continues to drink or use despite the negative effects • Organize around AOD use • risky use may overlap with dependence. • Some risky behaviors include:
Dependence • Constant use • Inability to take care of major responsibilities • Repeatedly using drugs in situations that are physically hazardous, • Legal problems • Their risky behavior may also escalate to things such as: • Dependent but “functioning”’ • House of cards • Walking on eggshells • Tolerance • Withdrawal
Addiction • Serious psychological and physical changes from constant heavy use of alcohol, drugs, or both. • Uncontrollable craving, seeking, and use, despite repeated negative consequences. • Addiction is a progressive, chronic, and fatal disease. If left untreated, it can only lead to:
Age at tobacco, alcohol, and cannabis dependence per DSM IV Addiction Is A Developmental Disease that starts in adolescence and childhood 1.8% 1.8% TOBACCO CANNABIS 1.6% 1.6% ALCOHOL 1.4% 1.4% 1.2% 1.2% 1.0% 1.0% % in each age group who develop first-time dependence 0.8% 0.8% 0.6% 0.6% 0.4% 0.4% 0.2% 0.2% 0.0% 0.0% 5 10 15 21 25 30 35 40 45 50 55 60 65 5 10 15 21 25 30 35 40 45 50 55 60 65 Age National Epidemiologic Survey on Alcohol and Related Conditions, 2003.
Addiction is a Developmental Disease: It Starts Early 67% 26% 5.5% 1.5% 12-17 <12 18-25 >25 First Marijuana Use, (Percent of Initiates)
Sample of 10,123 teens between the ages of 13 to 18 (2012) • 15 percent of the teens met the criteria for lifetime alcohol abuse, and 16 percent could be categorized as drug abusers • The median age for drug abuse with dependence to start was at the age of 14 • Archives of General Psychiatry)
Rats Exposed to Nicotine in AdolescenceSelf-Administer More Nicotine Than Rats First Exposed as Adults Collins et al, Neuropharmacology, 2004, Levin et al, Psychopharmacology, 2003
Stress Early physical or sexual abuse Witnessing violence Peers who use drugs Drug availability What EnvironmentalFactors Contribute to Addiction?
Advances in science have revolutionized our fundamental views of drug abuse and addiction.
Functionally… Dopamine D2 Receptors are Decreased by Addiction Cocaine Meth DA D2 Receptor Availability Alcohol Heroin Control Addicted
Your Brain on Drugs Today YELLOW shows places in brain where cocaine binds (e.g., striatum) Fowler et al., Synapse, 1989.
Effects of Drugs on Dopamine Release Accumbens Accumbens 400 1100 1000 900 DA 300 DOPAC 800 DA HVA 700 DOPAC HVA 600 % of Basal Release 200 % of Basal Release 500 400 300 100 200 100 0 0 0 1 2 3 4 5 hr 0 1 2 3 4 5 hr 250 Accumbens 250 Dose 200 Accumbens mg/kg 0.5 Caudate 200 mg/kg 1.0 150 mg/kg 2.5 mg/kg 10 150 100 % of Basal Release % of Basal Release 0 1 2 3 hr 100 0 0 0 1 2 3 4 5 hr Time After Drug Amphetamine Cocaine Morphine Nicotine Time After Drug Di Chiara and Imperato, PNAS, 1988
Changes in Attitudes Lead to Changes in Use Monitoring the Future Study, 2007.
Extended Abstinence is Predictive of Sustained Recovery After 5 years – if you are sober, you probably will stay that way. It takes a year of abstinence before less than half relapse Dennis et al, Eval Rev, 2007
Mmmmmmm?????? • Don’t necessarily believe all of this • Don’t necessarily believe a drug being legal means it’s ok • Cigarette smoking kills 5.5 million/year • Making weed legal is about the drug war not working, not about weed being ok for you • Just kidding….You should believe all of this….
Estimated Economic Cost to Society Due to Substance Abuse and Addiction: Illegal drugs: $181 billion/year Alcohol: $185 billion/year Tobacco: $158 billion/year Total: $524 billion/year Surgeon General’s Report, 2004; ONDCP, 2004; Harwood, 2000.
RESOURCES • School • Teachers • Coaches • Staff • School Counselors • ASACS Counselors • Community • Parents • Religious Leader • Coach • Counselors www.nida.nih.gov www.drugabuse.gov