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Fibrodysplasia Ossificans Progessiva (FOP)

Fibrodysplasia Ossificans Progessiva (FOP). http://www.youtube.com/watch?v=FsFPt0FATJc. What is it?. Extremely rare genetic connective tissue disorder Causes muscles, tendons and ligaments to become ossified when damaged

kenneth-mooney
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Fibrodysplasia Ossificans Progessiva (FOP)

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  1. FibrodysplasiaOssificansProgessiva(FOP) http://www.youtube.com/watch?v=FsFPt0FATJc

  2. What is it? • Extremely rare genetic connective tissue disorder • Causes muscles, tendons and ligaments to become ossified when damaged • Body forms second skeletal structure out of the body’s fibrous tissues, creating an internal straightjacket

  3. Causes/Symptoms • Genetic Mutation • caused by an autosomal dominant allele of the chromosomes • Deformed big toes • Tumor-like lumps that appear suddenly • Caused by bone morphogenetic protein 4

  4. Treatment • No current treatments but patients with FOP are advised to stay away from activities that can be hazardous that cause physical injury to the body • Steroid shots are used to help limit the abnormal bone growth.

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