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Transport of Oxygen and Carbon Dioxide

Transport of Oxygen and Carbon Dioxide. Lesson Objective : To describe and explain how oxygen and carbon dioxide are carried in blood and the effect of exercise. Blood Composition. What is in blood? 55% Plasma 45% Red Blood Cells (Erythrocytes) <1% White Blood Cells (Leukocytes) & Platelets.

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Transport of Oxygen and Carbon Dioxide

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  1. Transport of Oxygen and Carbon Dioxide Lesson Objective : To describe and explain how oxygen and carbon dioxide are carried in blood and the effect of exercise

  2. Blood Composition • What is in blood? • 55% Plasma • 45% Red Blood Cells (Erythrocytes) • <1% White Blood Cells (Leukocytes) & Platelets

  3. In Solution… 0.3ml per 100ml Not very soluble Average blood volume = 5 litres 15ml of oxygen 4 seconds Or 80 litres/minute at rest Physiologically important with Haemoglobin… Protein containing iron Sup up Oxygen carrying capacity 60-70 times 197ml/litre Oxygen Transport • KEY POINT • O2 transported in 2 ways • 3% In solution • 97% with haemoglobin

  4. Haemoglobin • Has 4 Iron molecules that can attract 4 oxygen molecules Hb4 + 4O2 Hb4O8 • Oxyhaemoglobin • Depends on partial pressure of oxygen

  5. In solution… 5% Physiologically important With water… 70% Carbonic Acid Slow process Carbonic Anhydrase speeds up x 5000 Carbon Dioxide Transport • With haemoglobin… • 25% • Carboaminohaemoglobin • Partial Pressure of O2 • Partial Pressure of CO2 CO2 transported in 3 ways

  6. Oxygen-Haemoglobin Dissociation Curve! Blood Oxygen Capacity = Hb (g) x O2 in Hb 15g of Hb / 100ml 1.34ml of oxygen / Hb g Answer is… 20ml of oxygen per 100ml of blood when breathing ambient air at sea level

  7. Your Mission Haemoglobin is not always saturated or associated with oxygen • Look at the ‘x’ axis on the following graph what does it show? • Draw a line up from 100 the axis to intersect the curve and then across to the ‘y’ axis. What is the % Saturation? • Do the same from 40. What is the % Saturation?

  8. You should have this…

  9. The Bohr-ing Effect of Exercise To get more oxygen dissociation we need the graph to move down and right • Increase in blood & muscle temperature • Decrease in PPO2 within muscle • Increase in PPCO2 within muscle • Increase in acidity THE BOHR EFFECT

  10. Pupil Tasksheet

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