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IUATLD-NAR 16 th Annual Conference San Antonio, TX February 25, 2012

A Targeted Testing Program Combined with 3 Months of Isoniazid and Rifapentine in Seattle’s Homeless Population. IUATLD-NAR 16 th Annual Conference San Antonio, TX February 25, 2012. Eyal Oren, PhD, MS.

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IUATLD-NAR 16 th Annual Conference San Antonio, TX February 25, 2012

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  1. A Targeted Testing Program Combined with 3 Months of Isoniazid and Rifapentine in Seattle’s Homeless Population IUATLD-NAR 16th Annual Conference San Antonio, TX February 25, 2012 Eyal Oren, PhD, MS This project was supported byWashington State Tuberculosis Control Cooperative Agreement Grant Award Number U52/CCU000510-28-1

  2. No conflicts of interest to disclose

  3. Background • 2002-2003 Homeless outbreak • Single strain identified for 44 (68%) of 65 homeless TB cases diagnosed during this period. • Concern about recent ongoing transmission among high-risk, mobile populations Homeless TB outbreak strain 2002-2010

  4. Objective • To provide targeted testing, diagnosis and treatment of LTBI among homeless individuals.

  5. Project Design May-December 2011 in King County, WA • Part 1: To test for LTBI and diagnose active TB • Six homeless sites • Quantiferon (QFT) blood test • Symptom screens for active TB • Variety of incentives and enablers • Part 2: To pilot new LTBI treatment regimen • Eligible LTBI receive weekly on-site 3HP DOPT • Weekly follow-up visit by field staff • Monthly check-in at TB clinic • Part 3: To assess feasibility and practicality of implementation • Documentation

  6. Results: Demographics

  7. Results: Screenings *Of those testing QFT positive **Original outbreak site

  8. Feasibility Considerations

  9. Project Team • Krista Powell and KirenMitruka, CDC • Masa Narita, Disease Control Officer • TB Control Program staff • Staff from partner sites and Healthcare for the Homeless

  10. Thank you!

  11. Next Steps • Continue to strengthen partnerships with sites (including Hispanic, Women) • Reach out to other sites serving homeless to continue targeting LTBI • Incentives and enablers for high-risk LTBI • Partner with other providers to increase service to this community • Assess 3HP treatment outcomes • Roll out 3HP more broadly

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