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HIV in Brazil Daniela Zilio Larentis Infectious Disease Resident at HCPA. Population : 191.000.000 (2010 ). 630.000 living with HIV ( 2009). AIDS: 592.914 (2009). Number of deaths : 217.091. Reported cases/ year : 33-35.000. Epidemiology (1980-2009). Men/woman ratio: 1,5;
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HIV in Brazil Daniela ZilioLarentis InfectiousDiseaseResidentat HCPA
Population: 191.000.000 (2010) 630.000 living with HIV (2009) AIDS: 592.914 (2009) Numberofdeaths: 217.091 Reported cases/year: 33-35.000
Epidemiology (1980-2009) Men/woman ratio: 1,5; • Most affected strata between 30-49y, increasing in older than 50 y; • 47,7 % of infected are white ethnicity; • Pregnant woman: 54.218 20-29 y Ministério da Saúde 2010
Source of HIV acquisition (1980-2010) - Vertical transmission: 4.181
Co-infection HIV/TBC % BK performed Coinfection
HAART • 1700 euros/year/pacient (2002-2007) with treatment, • Universal access since 1996, • When start treatment: 1. Symptomatics 2. Asymptomatics - CD4 >500: no ART - CD4 350-500: HCV, HBV, nephropathy, any cancer, VL> 100.000, high risk for CVD, - CD4 <350: ART 3. Pregnancy
Brazilianguidline for treatment - NRTI ZDV, 3TC, TDF - ddI, d4T, ABC -NNRTI EFZ, - NVP • PI ATV, LOP/r - DRV, IDV, APV -Rescue therapy: T20, raltegravir, etravirina, maravirock
Appointment: CD4, CV, Use of HAART, Side efects of HAART, Genotyping, Advices (protect sex, immunization).