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Rehospitalization following vagal nerve stimulator implant. Paul Kalanithi, MD, Bob Arrigo, BS, Maxwell Boakye, MD, FACS Outcomes Research Center Stanford University Department of Neurosurgery. Disclosures: None. VNS FOR EpiLEPSY.
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Rehospitalization following vagal nerve stimulator implant Paul Kalanithi, MD, Bob Arrigo, BS, Maxwell Boakye, MD, FACS Outcomes Research Center Stanford University Department of Neurosurgery Disclosures: None
VNS FOR EpiLEPSY • Only 1 prior large database study on vagal nerve stimulation – only inpatient • Rehospitalization rates likely to become quality measure • This study provides California data regarding 1 year follow-up data on rehospitalization rates, frequency, charges and complications of vagal nerve stimulation for epilepsy
METHODS • Data Source • Healthcare Cost and Utiliation Project’s California State Inpatient Databases (CA-SID), Ambulatory Surgery Database • collects ICD-9, CPT, and other administrative data on hospitalizations in California • HCUP verification for longitudinal analysis • Inclusion/Exclusion criteria • All patients from 2005-2007 with: • With primary procedure codes for ICD-9 04.92, 04.93, 86.94, 86.05; CPT 64573, 61885, 64585, 61888 • Primary diagnosis code for epilepsy ICD-9 345.x • Variables: age, co-morbidity, gender, race, hospital size, county, • Outcomes: 1 year rehospitalizations and reoperations, 30 day complications, mortality, suicide rates
Statistical Analysis • Predictors of in-hospital complication and adverse disposition were identified using a univariate and multivariate logistic regression model. • P-value < 0.05 or odds ratio excluding 1.00 were accepted as significant
LOW COMPLICATIONS, MORTALITY 30 Day Complications: 0.4% - 1 pulmonary event 30 Day Mortality: 0%
REHOSPITALIZATION RATES • One year rehospitalization rates: • 118 • 45% • One Year Suicide Attempt Rate: • 1.8%
REOPERATION RATES • One year reoperation rate: 5.7% • VNS system removals: 5 • IPG replacements: 6 • IPG removals: 4 • Diagnoses: Infection 2.7% Device Failure 1.5%
Methodologic weaknesses • Only assesses mortality/suicide from clinical settings • Cannot assess decision for operation/other clinical factors • Limitations of ICD-9/CPT codes • No functional outcomes
SUMMARY • VNS overall a very safe procedure • Rehospitalization rates comparable to other procedures • Reoperation rates 5.7% at 1 year • HCUP databases can be used for longitudinal data across multiple care delivery settings