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LUNG TRANSPLANTATION

LUNG TRANSPLANTATION. Pediatric Recipients. ISHLT. 2009. RECIPIENT AGE DISTRIBUTION FOR PEDIATRIC LUNG RECIPIENTS - NUMBER (Transplants: January 1986 - June 2008). ISHLT. 2009. Analysis includes living donor transplants.

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LUNG TRANSPLANTATION

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  1. LUNG TRANSPLANTATION Pediatric Recipients ISHLT 2009

  2. RECIPIENT AGE DISTRIBUTION FOR PEDIATRIC LUNG RECIPIENTS - NUMBER (Transplants: January 1986 - June 2008) ISHLT 2009 Analysis includes living donor transplants

  3. RECIPIENT AGE DISTRIBUTION FOR PEDIATRIC LUNG RECIPIENTS - PERCENTAGE(Transplants: January 1986 - June 2008) ISHLT 2009 Analysis includes living donor transplants

  4. DONOR TYPE DISTRIBUTION BY YEAR OF TRANSPLANT FOR PEDIATRIC LUNG RECIPIENTS (Transplants: 1986-2007) NOTE: This figure includes only the lung transplants that are reported to the ISHLT Transplant Registry. As such, the presented data may not mirror the changes in the number of lung transplants performed worldwide. ISHLT 2009 Analysis includes living donor transplants

  5. DONOR TYPE DISTRIBUTION BY RECIPIENT AGE GROUP WITHIN ERA FOR PEDIATRIC LUNG RECIPIENTS (Transplants: January 1986 - June 2008) ISHLT 2009 Analysis includes living donor transplants

  6. AGE DISTRIBUTION FOR DONORS OFPEDIATRIC LUNG RECIPIENTS(Transplants: January 1986 - June 2008) ISHLT 2009

  7. AGE DISTRIBUTION OF PEDIATRIC LUNG RECIPIENTSBy Year of Transplant NOTE: This figure includes only the pediatric lung transplants that are reported to the ISHLT Transplant Registry. Therefore, these numbers should not be interpreted as the rate of change in pediatric lung procedures performed worldwide. ISHLT 2009 Analysis includes living donor transplants

  8. NUMBER OF CENTERS REPORTING PEDIATRIC LUNG TRANSPLANTS ISHLT 2009 Analysis includes living donor transplants

  9. NUMBER OF CENTERS REPORTING PEDIATRIC LUNG TRANSPLANTS BY CENTER VOLUME ISHLT 2009 Analysis includes living donor transplants

  10. PEDIATRIC LUNG TRANSPLANTATION: Indications (Transplants: January 1990 – June 2008) ISHLT 2009 Analysis includes living donor transplants

  11. PEDIATRIC LUNG TRANSPLANTATION:Other Indications (Transplants: January 1990 – June 2006) ISHLT 2009 Analysis includes living donor transplants Last updated based on data as of December 2006

  12. PEDIATRIC LUNG TRANSPLANTATION: Other Indications (Transplants: January 1990 – June 2006) ISHLT 2009 Analysis includes living donor transplants Last updated based on data as of December 2006

  13. PEDIATRIC LUNG TRANSPLANTATION: Other Indications (Transplants: January 1990 – June 2006) ISHLT 2009 Analysis includes living donor transplants Last updated based on data as of December 2006

  14. DIAGNOSIS IN PEDIATRIC LUNG RECIPIENTSBY YEAR OF TRANSPLANTAge: 12-17 Years ISHLT 2009 Analysis includes living donor transplants

  15. PEDIATRIC LUNG TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2008 ISHLT 2009 Analysis includes living donor transplants

  16. PEDIATRIC LUNG TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2008 • NOTE: Unknown diagnoses were excluded from this tabulation. • Total number of transplants reported: • Europe = 171 • North America = 443 • Other = 35 ISHLT 2009 Analysis includes living donor transplants

  17. PEDIATRIC LUNG TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2008 • NOTE: Transplants with unknown donor age and living donor transplants were excluded from this tabulation. • Total number of transplants reported: • Europe = 181 • North America = 443 • Other = 35 ISHLT 2009

  18. LUNG TRANSPLANTATIONKaplan-Meier Survival by Age Group (Transplants: January 1990 - June 2007) ISHLT 2009

  19. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Procedure Type (Transplants: January 1990 - June 2007) ISHLT 2009

  20. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival for Congenital Diagnoses (Transplants: January 1990 – June 2007) ISHLT 2009

  21. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Age Group (Transplants: January 1990 - June 2007) ISHLT 2009

  22. PEDIATRIC LUNG TRANSPLANTATIONConditional Kaplan-Meier Survival by Age Group(Transplants: January 1990 - June 2007) ISHLT 2009

  23. PEDIATRIC LUNG TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: January 1988 - June 2007) ISHLT 2009

  24. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Donor Type for Recipients Age 12-17 Years(Transplants: January 1990 - June 2007) ISHLT 2009

  25. PEDIATRIC LUNG RE-TRANSPLANTS Between January 1994 and June 2008 Time Between Previous and Current Transplant ISHLT 2009

  26. PEDIATRIC LUNG RETRANSPLANTSSurvival for Transplants Performed Between January 1994 and June 2007 ISHLT 2009

  27. PEDIATRIC LUNG RECIPIENTS Functional Status of Surviving Recipients(Follow-ups: April 1994-June 2008) ISHLT 2009

  28. PEDIATRIC LUNG RECIPIENTSFunctional Status of Surviving RecipientsFor the Same Patients(Follow-ups: April 1994-June 2008) ISHLT 2009

  29. PEDIATRIC LUNG RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2008) ISHLT 2009

  30. PEDIATRIC LUNG RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2008) ISHLT 2009

  31. PEDIATRIC LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 and June 2008 ISHLT 2009 Analysis is limited to patients who were alive at the time of the follow-up

  32. PEDIATRIC LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2001 - June 2007) ISHLT 2009 Analysis is limited to patients who were alive at the time of the follow-up

  33. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival Stratified by Induction Use (Transplants: January 2001 - June 2007) ISHLT 2009

  34. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 – June 2008) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2009 Analysis is limited to patients who were alive at the time of the follow-up

  35. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 – June 2008) 1 Year Follow-up (N = 272) 5 Year Follow-up (N = 117) NOTE: Different patients are analyzed in Year 1 and Year 5 NOTE: 4% of patients were on both calcineurin inhibitors at different point during the year; these patients are not counted in either group. And 1% (2 patients) was on neither drugs during the year. In the 5-year tabulations, 13% were reported to be on both drugs during the year and 1% (1 patient) was reported to be on neither drugs. ISHLT 2009 Analysis is limited to patients who were alive at the time of the follow-up

  36. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-up Report (Follow-ups: January 2001 – June 2008) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2009 Analysis is limited to patients who were alive at the time of the follow-up

  37. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2008) ISHLT 2009

  38. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2008) ISHLT 2009

  39. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 7 Years Post-Transplant (Follow-ups: April 1994 - June 2008) ISHLT 2009

  40. Freedom from Bronchiolitis Obliterans Syndrome For Pediatric Lung Recipients(Follow-ups: April 1994 - June 2008) ISHLT 2009

  41. Freedom from Bronchiolitis Obliterans Syndrome For Pediatric Lung Recipients by Induction Use (Follow-ups: April 1994 - June 2008) ISHLT 2009

  42. Freedom from Severe Renal Dysfunction*For Pediatric Lung Recipients(Follow-ups: April 1994 - June 2008) ISHLT 2009

  43. MALIGNANCY POST-LUNG TRANSPLANTATION FOR PEDIATRICSCumulative Incidence for Survivors(Follow-ups: April 1994 - June 2008) ”Other” includes Liver and primitive neuroectodermal tumor. ISHLT 2009

  44. Freedom from MalignancyFor Pediatric Lung Recipients (Follow-ups: April 1994 - June 2008) ISHLT 2009

  45. PEDIATRIC LUNG TRANSPLANT RECIPIENTS: Cause Of Death(Deaths: January 1992- June 2008) ISHLT 2009

  46. PEDIATRIC LUNG TRANSPLANT RECIPIENTS: Other Cause Of Death(Deaths: January 1992- June 2006) ISHLT 2009 Last updated based on data as of December 2006

  47. PEDIATRIC LUNG TRANSPLANT RECIPIENTS: Relative Incidence of Leading Causes of Death(Deaths: January 1992 - June 2008) ISHLT 2009

  48. PEDIATRIC LUNG TRANSPLANT RECIPIENTS (1/1990-6/2007) Risk Factors For 1 Year Mortality/Graft Failure N=738 ISHLT 2009

  49. PEDIATRIC LUNG TRANSPLANT RECIPIENTS (1/1990-6/2003) Risk Factors For 5 Year Mortality/Graft Failure N=527 ISHLT 2009

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