1 / 1

RNAi

Supplementary Figure 2. A. TOTAL. MITO. C. Pin1. RNAi. C. Pin1. RNAi. Doxorubicin. MITO. TOTAL. –. +. –. +. MITO. TOTAL. Etoposide. –. +. –. +. –. +. –. +. –. +. –. +. WB: p53. Pin1. WB: p53. WB: Pin1. ACTIN. WB: VDAC. WB: VDAC. WB: PCNA. WB: PCNA. D. B.

koen
Download Presentation

RNAi

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Supplementary Figure 2 A TOTAL MITO C Pin1 RNAi C Pin1 RNAi Doxorubicin MITO TOTAL – + – + MITO TOTAL Etoposide – + – + – + – + – + – + WB: p53 Pin1 WB: p53 WB: Pin1 ACTIN WB: VDAC WB: VDAC WB: PCNA WB: PCNA D B Etoposide MITOCHONDRIA Thymus BoneMarrow P#1 P#2 RNAi C + + 5Gy γ-IR + + IVTT MBPp53 GST Pin1 Doxorubicin GST BclXL + + + +/+ –/– +/+ –/– Pin1 GST WW GST WB: p53 WB: CLEAVED CASPASE-3 MBP MBP p53 ISOMERIZATION INPUT Pin1 WW GST Pin1 WW GST WB: Pin1 WB: p53 WB: p53 WB: GST WB: VDAC WASH WB: Pin1 WB: PIN1 inputs – p53 WT S46A GST BclXL WB: PCNA HA-Ub + + + + + WB: MBP WB: ACTIN WB: actin Pin1 – + – + – SDS PAGE E C WB: HA IP: p53 WB: p53 – monoUb HA/p53

More Related