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Experimental Research Strategies. 2. Treatment Moderator Candidates. Patient characteristicsDemographicsPretreatment severityComorbid conditionsPersonality traits. Experimental Research Strategies. 3. Treatment Moderator Candidates . Therapist characteristicsProfessional affiliationLevel of ex
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1. Experimental Research Strategies 1 Treatment Moderator “A categorical or continuous variable that affects the direction or strength of the relation between treatment and one or more clinical outcomes.”
2. Experimental Research Strategies 2 Treatment Moderator Candidates Patient characteristics
Demographics
Pretreatment severity
Comorbid conditions
Personality traits
3. Experimental Research Strategies 3 Treatment Moderator Candidates Therapist characteristics
Professional affiliation
Level of experience
Therapeutic skill variable
Warmth
Empathy
Case formulation skills
Instigation skills
Other
4. Experimental Research Strategies 4 Examples of Moderator Effects Moderators of overall clinical response
Analytic strategy:
Demonstrated relationship between moderator and level of improvement
Relationship holds across conditions (no moderator by condition interaction)
Example:
Patients displaying high levels of optimism (moderator) are more likely to improve regardless of whether they receive active treatment, placebo, or no treatment
5. Experimental Research Strategies 5 Example of Overall Clinical Response