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SCHISTOSOMIASIS IN AFRICA. Tymeka Lewis, Ph.D. student Walden University PUBH 8165-1 Instructor: Dr. Shana Morrell Spring, 2009. LEARNING OBJECTIVES. Schistosomiasis Definition Rate of the disease Symptoms Treatments Prevention. WHAT IS SCHISTOSOMIASIS?.
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SCHISTOSOMIASISIN AFRICA Tymeka Lewis, Ph.D. student Walden University PUBH 8165-1 Instructor: Dr. Shana Morrell Spring, 2009
LEARNING OBJECTIVES • Schistosomiasis • Definition • Rate of the disease • Symptoms • Treatments • Prevention
WHAT IS SCHISTOSOMIASIS? • Bilharzia or snail fever (CDC, 2008) • 200 million people are infected, mainly in Africa (CDC, 2008) • 20 million people disabled (EPA, 2008) • 280,000 die each year (EPA, 2008) • Contaminated freshwater with snails carry the disease (CDC, 2008) CDC. (2008). Schistosomiasis. Retrieved April 13, 2009, from http://www.cdc.gov/ncidod/dpd/parasites/schistosomiasis/default.html EPA. (2008). Scientist identify new leads for treating parasitic worm disease. Retrieved April 13, 2009, from http://www.eps.gov/aging/press/othernews/2008/2008
HOW YOU GET IT? • Contact with contaminated freshwater with Schistosoma eggs • Eggs hatch • Parasites grows in snails • Parasites leaves snails • Parasites enters a person’s skin (CDC, 2008) CDC. (2008). Schistosomiasis: Fact sheet. Retrieved April 13, 2009, from http://www.cdc.gov. Figure 1. Wikipedia. Skin vesicales on the forearem, created by the penetration of Schistosoma.
MAIN FORMS OF HUMANSCHISTOSOMIASIS S. mansoni Figure 2. Wikipedia. S. haematobium Figure 3. Wikipedia.
SYMPTOMS • Rash or itchy skin • Fever or chills • Cough • Muscle aches • Inflammation -swelling and tenderness of the liver CDC. (2008). Schistosomiasis: A fact lost boys and girls of Sudan. Retrieved April 13, 2009, from http://www.cdc.gov/ncidod/dq/refugee/lostboysandgirlssudan/schistosomiasis_fact_sheet.html
TREATMENT FOR SCHISTOSOMIASIS • Praziquantel – treats all forms (CDC, 2008) • Oxamniquine – treats intestinal (CDC, 2008) • Metrifonate – treats urinary (WHO, 2007) • No vaccine (CDC, 2008) CDC. (2008). Schistosomiasis: A fact sheet for the lost boys and girls of Sudan. Retrieved April 13, 2009, from http://www.cdc.gov/ncidod/dq/refugee/lostboysandgirlssudan/schistosomiasis_fact_sheet.html WHO. (2007). Schistosomiasis. Retrieved April 13, 2009 from http://www.microbiologybytes.com/introduction/Schisto.html Figure 4. Generic Biltricide (Praziquantel ) 600 mg Tablets
PREVENTION • Avoid freshwater • washing, swimming, wading or bathing • Drink safe water • Heat bath water • Use toilets CDC. (2008). Schistosomiasis. Retrieved April 13, 2009 from http://www.cdc.gov Figure 5. Photo Disc Image.
WHO DOES IT MAINLY AFFECT?CHILDREN! Figure 6. Girl getting water. Figure 7. Kids playing in water.
REDUCING THE DISEASE IN AFRICA • Health education • Control of freshwater snails • Supply of water • Low cost of medicine • Management of the environment • Improve sanitation WHO. (2007). Schistosomiasis. Retrieved April 13, 2009 from http://www.microbiologybytes.com/introduction/Schisto.html Figure 8. WHO. New parasites (cercariae)
CONCLUSION • Schistosomiasis is caused by parasitic flatworms (CDC, 2008). • A person become infected with schistosomiasis when contaminated freshwater where snails carry schistosomes gets on the skin (CDC, 2008). • There are two main forms of schistosomiasis (Britannica, 2009).
CONCLUSION • Praziquantel is the drug that treats it (CDC, 2008). • DON’T swim, wade, bath or wash in freshwater. • 66 million children are affected with schistosomiasis (WHO, 2007).
CONCLUSION • To reduce incidence in African communities • Health education should be provided • Freshwater snails should be under control • Supply of water should be tested • Praziquantel should be provided to children annually • Management of the environment including improved sanitation (pipes)
REFERENCES CDC. (2008). Schistosomiasis. Retrieved April 13, 2009, from http://www.cdc.gov. CDC. (2008). Schistosomiasis: A fact sheet for the lost boys and girls of Sudan. Retrieved April 13, 2009, from http://www.cdc.gov/ncidod/dq/refugee/lostboysandgirlssudan/schistosomiasis_fact_sheet.html CDC. (2009). Prevention of specific infectious diseases. Retrieved April 13, 2009, from http://wwwn.cdc.gov.travel.yellowBookCH4-Schistosomiasis.aspx CDC. (2009). Schistosomiasis. [Online Image]. Retrieved April 13, 2009, from Wikipedia. http://en.wikipedia.org Clements, A., Garba, A., Sacko, M., Toure., Dembele, R., Landoure, A., Bosque-Olivia, E., Gabrielli, A. F., & Fenwick, A. (2008). Mapping the probability of schistosomiasis and associated uncertainty, West Africa. Emerging Infectious Diseases, 14(10), 1629-1632. DOI: 10.3201/eid1410.080366
REFERENCES CONTINUED Deganello, R., Cruciani, M., Beltramello, C., Duncan, O., Oyugi, V., & Montresor, A. (2007). Schistosoma hematobium and S. mansoni among children, Southern Sudan. Emerging Infectious Diseases, 13(10), 1504-1506. Doumenge, J. P., Mott, K. E., Villenave, C. D., Perrin, O. C., & Reaud-Thomas, G. (1987). Atlas of the global distribution of schistosomiasis. World Health Organization. Retrieved April 13, 2009, from http://www.who.int/wormcontrol/documents/maps/en/contents.pdf EPA. (2008). Scientist identify new leads for treating parasitic worm disease. Retrieved April 13, 2009, from http://www.epa.gov/aging/press/othernews/2008/2008_0316_ons_1.htm Generic Biltricide (Praziquantel). [Online Image]. Retrieved April 13, 2009, from http://www.generics.ws Meltzer, E., Artom, G., Marva, E., Assous, M. V., Rahav, G., & Schwartz, E. (2006). Schistosomiasis among travelers: New aspects of an old disease. Emerging Infectious Diseases, 12(11), 1696-1700.
REFERENCES CONTINUED Photos Disc Image. [Online Image]. Water boiling in pot on stove. Retrieved April 13, 2009, from http://images.google.com Schistosomiasis. (2009). In Encyclopedia Britannica. Retrieved April 14, 2009, from Encyclopedia Britannica http://www.britannica.com/EBchecked/topic/527459/schistosomiasis Taylor, M. (2008). Global trends in schistosomiasis control.World Health Organization, 86(10), 738. doi 10:2471/BLT.08.058669 WHO. (2007). Schistosomiasis. Retrieved April 13, 2009, from http://www.microbiologybytes.com/introduction/Schisto.html WHO. Schistosomiasis. [Online Image]. Retrieved April 13, 2009, from World Health Organization. http://www.microbiologybytes.com Wikipedia. Schistosomiasis. [Online Image]. Retrieved April 13, 2009, from Wikipedia. http://en.wikipedia.org
FOR FURTHER READING • CDC. (2008).. Schistosomiasis. Retrieved April 13, 2009, from http://www.cdc.gov. • Centron, M. S., Chitsulo, L., & Sullivan, J. J. (1996). Schistosomiasis in Lake Malawi. Lancet, 348, 1274-1278. • Photograhy.com. [Online Image]. Retrieved April 13, 2009 from Photography.com • Pritt, B. S., & Clark, C. G. (2008). Amebiasis. Mayo Clinic Proceedings, 83(10), 1154-1160. • Schwartz, E., Kozarsky, P., Wilson, M., & Centron, M. (2005). Schistosome infection among river rafters on Omo River, Ethiopia. Journal Travel Medicine, 12, 3-8. • World Health Organization. (1993). The control of schistosomiasis: Second report of the WHO Expert Committee. WHO Technical Report Series 830. Geneva.