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Physical and Psychological Sequelae of Breast Cancer in Men. Kathryn J. Ruddy, MD MPH, 1 Anita Giobbie-Hurder, MS, 1 Sharon Giordano, MD, 2 Shari Goldfarb, MD, 3 Sandra Kereakoglow, BA, 1 Eric P. Winer, 1 MD, Ann H. Partridge, MD MPH 1
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Physical and Psychological Sequelae of Breast Cancer in Men • Kathryn J. Ruddy, MD MPH,1 Anita Giobbie-Hurder, MS,1 Sharon Giordano, MD,2 Shari Goldfarb, MD,3 Sandra Kereakoglow, BA,1Eric P. Winer,1 MD, Ann H. Partridge, MD MPH1 • 1Dana-Farber Cancer Institute, Boston, MA; 2M.D. Anderson Cancer Center, Houston, TX; 3Memorial Sloan Kettering Cancer Center, New York, NY Background Little is known about the physical and emotional health of men with breast cancer; data are also lacking regarding their informational and supportive care needs Aim To assess attitudes, symptoms, experiences, and health perceptions in men with a history of breast cancer • Methods • Study Setting • Online survey recruiting participants via three websites focused on male breast cancer: www.outoftheshadowofpink.comwww.malebreastcancer.orgwww.malebreastcancer.ca • Measurements • Anxiety and depression over prior month using Hospitalized Anxiety and Depression Scale (HADS), scored 0-21 for each subscale • Health-related quality of life (QOL) over prior 7 days using Functional Assessment of Cancer Therapy-Breast (FACT-B), scored 0-144 • Hormonal and sexual symptoms over prior 4 weeks using the Expanded Prostate Cancer Index Composite (EPIC) Hormonal and Sexual Scales, each scored 0-100 • Higher scores on the HADS indicate more symptoms; higher scores on FACT-B and EPIC imply better QOL • History of genetic and fertility counseling Limitations Potential for sample bias, recall bias, and unmeasured confounders • Conclusions • Male breast cancer survivors experience substantial symptoms • Hormonal symptoms are prevalent in male breast cancer survivors; in men without cancer, mean EPIC Hormonal Score is 91.7 (SD 9.7) • Sexual functioning may be impaired in male breast cancer survivors; in men without cancer, mean EPIC Sexual Score is 61.4 (SD 23.6) • We plan to use data from this pilot study to inform a larger study and develop targeted interventions to reduce symptom burden in male breast cancer survivors