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Pattern of p63 mutations and their phenotypes—update

Pattern of p63 mutations and their phenotypes—update. American Journal of Medical Genetics Part A Volume 140A, Issue 13, pages 1396-1406, 11 MAY 2006 DOI: 10.1002/ajmg.a.31271 http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.31271/full#fig1. Tutti gli epiteli stratificati

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Pattern of p63 mutations and their phenotypes—update

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  1. Pattern of p63 mutations and their phenotypes—update American Journal of Medical Genetics Part AVolume 140A, Issue 13, pages 1396-1406, 11 MAY 2006 DOI: 10.1002/ajmg.a.31271http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.31271/full#fig1

  2. Tutti gli epiteli stratificati (Epidermide, Cornea, Prostata, Mammella, Vescica, etch) sono colpiti nei topi p63 KO.

  3. terminal differentiation response to DNA damage p63 p53 CEBPs growth/differentiation cell cycle RB1 E2Fs NOTCH1 SMAD PPARs LEF1 SALL4 permeability barrier wound healing TGFb and WNT signaling stemness

  4. DNp63 TAp63

  5. ? ? ?

  6. DNp63 TAp63 TAp63

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