1 / 16

Review Beta Oxidation

Review Beta Oxidation. Protein Metabolism. 20 aa’s that combine in unique arrangements to form individual proteins. Amino Acids. Amino radical (NH 2 ) Carboxyl group (COOH) The side chain (carbon, hydrogen, sometimes sulfur or nitrogen) is what gives it specific characteristics

kwhitener
Download Presentation

Review Beta Oxidation

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Review Beta Oxidation

  2. Protein Metabolism

  3. 20 aa’s that combine in unique arrangements to form individual proteins

  4. Amino Acids • Amino radical (NH2) • Carboxyl group (COOH) • The side chain (carbon, hydrogen, sometimes sulfur or nitrogen) is what gives it specific characteristics • 10 aa’s are essential, cannot be synthesized in the body

  5. All aa’s become part of the amino acid pool: three compartments • blood • liver • skeletal muscle

  6. aa’s in the compartments are in equilibrium; change one, change all, blood is the communicator • if one compartment is low, can replenish from another: glucose-alanine cycle

  7. aa’s brought to liver, converted to glucose (gluconeogenesis) and released in blood for delivery to working muscle

  8. aa’s in muscle are converted to alanine, carried to liver, where amino radical is removed (deamination) carbon skeleton is converted to glucose

  9. After 4 hours of continuous exercise, liver’s output of alanine-derived glucose accounts for 45% of total hepatic glucose

  10. As intensity of exercise increases; so does alanine release from exercising muscles (7X)

  11. Energy derived from glucose-alanine cycle can account for 10-15% of the total energy requirement

  12. Amino acid metabolism can be divided as • disposal of the alpha-amino group (via alpha-ketogluterate to glutamate to ammonia to urea) • carbon skeletons are converted to intermediates of metabolism

  13. If energy state is high: convert to acetyl-CoA and stored as fat

  14. If energy state is low: catabolized to support demand (exercise) for energy

  15. Alanine, via pyruvate, yields 15 ATP

More Related