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Quad-Rat Vitals Monitor

Quad-Rat Vitals Monitor. Advisor: Paul Thompson Client: Dr. Alex Converse. Overview. PET Imaging Requirements Existing Devices Previous Semester’s Work Pulse Oximeter Probe Design Options LabVIEW Interface Design Options Where do we go from here? Acknowledgments. PET Imaging of Rats.

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Quad-Rat Vitals Monitor

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  1. Quad-Rat Vitals Monitor Advisor: Paul Thompson Client: Dr. Alex Converse

  2. Overview • PET Imaging • Requirements • Existing Devices • Previous Semester’s Work • Pulse Oximeter Probe Design Options • LabVIEW Interface Design Options • Where do we go from here? • Acknowledgments

  3. PET Imaging of Rats • Positron emission tomography (PET) scans to monitor location of tracers in rats • Client scans four anesthetized rats at a time • Needs to monitor the rats’ vitals http://homepages.cae.wisc.edu/~bme300/rat_monitor _s09/reports/FinalPaperSpring09.pdf

  4. Requirements: Quads Vitals Monitor • Client needs to simultaneously monitor four rats • SpO2levels, accuracy of ±2% • Heart rates up to 500 beats per minute • Respiratory rates of 20 to 30 breaths per minute • Rectal temperatures of 93 - 100° F • Non-invasive probes and user-friendly interface

  5. Existing Devices • Existing devices: • Client currently uses rudimentary devices to monitor vitals • Available: Pulse oximeter for mice and rats • Over $7000, one rat at a time http://www.starrlifesciences.com/mri.html

  6. Previous Semester’s Work • Developed circuit for detecting breathing rate using force sensing resistor • Designed and calibrated thermistor to detect temperature • Designed Graphical User Interface (GUI) in LabVIEW displaying breathing rate and temperature • Attempted to reverse engineer existing Pulse Oximeter Force sensing resistor LabVIEW interface

  7. General Probe Requirements • Applicable for rats of varying size • Reusable • Sufficient blocking of ambient light • Compatible LED and Photodiode http://www.oximetry.org/pulseox/principles.htm

  8. Foot Clip • Pros: • Similar to current device • Easy to reposition • Positioned far from the head • Cons: • Can displace easily • Risk of LED/Photodiode misalignment • Potential to apply excessive pressure

  9. Foot Wrap • Pros: • No displacement once attached • Alignment of LED/Photodiode maintained throughout testing • Cons: • Not adjustable • More involved cleaning process

  10. Tail Clip • Pros: • Easy to attach • No confusion over placement location • Adjustable • Cons: • May interfere with catheter in tail • Potential to apply excessive pressure

  11. Four Corners with Buttons Full display

  12. Four Corners with Buttons • Pros: • Logical layout • Important information visible • Cons: • Extra clicking • History graphs incomparable • Less robust A sample quarter of the final display

  13. Tab Interface • Pros: • Uncluttered interface • Easy to program • Cons: • Inefficient • Data hard to compare Full display

  14. Four Corners with Histories Full display

  15. Four Corners with Histories • Pros: • All data on one screen • Easy to compare trends • Cons: • Cluttered interface • Tiny on small screen A sample quarter of the final display

  16. Where do we go from here? • Finish LabVIEW GUI • Determine how data will be collected from Pulse Oximeter • Design pulse-ox probe to fit rat’s hind paw • Integrate with signal received from Graduate Students’ circuit • Print circuit boards • Fabricate housing apparatus

  17. Acknowledgements • Professor Paul Thompson • Dr. Alex Converse • Amit Nimunkar • Tim Balgemann • Liz Ahlers • Nate Werbeckes

  18. Questions?

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