It all Starts with the Neuron

1. It all Starts with the Neuron http://videos.howstuffworks.com/health/human-brain-videos-playlist.htm#video-6080

2. Neuron Structure Neurons do NOT touch each other- the space in between is called synaptic cleft.

3. Neural Bases of Psychology: The Structure of a Neuron

4. How a Neuron Fires It is an electrochemical process • Electrical inside the neuron • Chemical outside the neuron (in the synapse in the form of a neurotransmitter). • The firing is call Action Potential.

5. Neural Bases of Psychology: Neural Communication • Within a neuron, communication occurs through an action potential (neural impulse that carries information along the axon of a neuron).

6. Neural Bases of Psychology: Neural Communication • Within a neuron, communication occurs through an action potential (neural impulse that carries information along the axon of a neuron).

7. The All-or None Response • The idea that either the neuron fires or it does not- no part way firing. • Like a gun

8. Steps of Action Potential • Dendrites receive neurotransmitter from another neuron across the synapse. • Reached its threshold- then fires based on the all-or-none response. • Opens up a portal in axon, and lets in positive ions (Sodium) which mix with negative ions (Potassium) that is already inside the axon (thus Neurons at rest have a slightly negative charge). • The mixing of + and – ions causes an electrical charge that opens up the next portal (letting in more K) while closing the original portal. • Process continues down axon to the axon terminal. • Terminal buttons turns electrical charge into chemical (neurotransmitter) and shoots message to next neuron across the synapse.

10. Action Potential

11. How Neurons Communicate

13. Which sentence most closely describes neural transmissions? • A. an electric charge is created in the neuron, the charge travels down the cell, and chemicals are released that cross the synapse to the next cell • B. a chemical change occurs within the cell, the change causes an electric charge to be produced and the charge jumps the gap between the nerve cells. • C. the electric charge produced chemically inside a group of neurons causes chemical changes in surrounding cells • D. neurotransmitters produced in the hindbrain are transmitted to the forebrain, causing electric

14. Neurotransmitters • Chemical messengers released by terminal buttons through the synapse. • We should know at least 6 types and what they do.

15. Neurotransmitters

16. Acetylcholine • Its function is motor movement and maybe memory. To much and you will…. Not enough and you will…. Lack of ACH has been linked to Alzheimer’s disease.

17. Dopamine • Its function is motor movement and alertness. Lack of dopamine is associated with Parkinson’s disease. Overabundance is associated with schizophrenia.

18. PET scan • Parkinsons • Muscle rigidity • Tremors • Speech slur • Difficult gait • Before/After medicine www. Epub.org What type of scan Is this?

19. Serotonin • Function deals with mood control. Lack of serotonin has been linked to depression.

20. Endorphins • Function deals with pain control. We become addicted to endorphin causing feelings.

21. What are agonists and antagonists? • They are drugs • Agonists mimic neurotransmitters. Example: Nicotine is an ACh agonist • Antagonists block neurotransmitters: • Ex: curare is an antagonist for ACh (paralyzes you)

22. Agonists and Antagonists

23. You eat some bad Chinese food and feel you are losing control of your muscles. The bacteria you ingested from the food most likely interferes with the use of: • A. serotonin • B. insulin • C. acetylcholine • D. Thorazine • E. adrenaline

24. What is reuptake? • The mopping up of excess neurotransmitter. • Excess neurotransmitters in the synapse are reabsorbed into the sending neurons. • This process applies the brakes on neurotransmitter action.

25. How does Prozac work? • It is a serotonin reuptake inhibitor.

26. How does Cocaine work? The white cocaine blocks the reuptake of dopamine.

27. Types of Neurons Sensory Neurons Motor Neurons Inter Neurons

28. Kinds of Neurons http://videos.howstuffworks.com/health/human-brain-videos-playlist.htm#video-6081 • Motor Neuronscarry outgoing information from the CNS to muscles and glands. • Interneurons connect the two neurons. • Sensory Neurons carry incoming information from the sense receptors to the CNS. Sensory Neuron (Bipolar) Motor Neuron (Multipolar) Interneuron Neuron (Unipolar)

29. Divisions of the Nervous System “para” like A parachute

30. Peripheral Nervous System Somatic Nervous System: • Controls voluntary muscle movement. • Uses motor (efferent) neurons. Autonomic Nervous System: • Controls the automatic functions of the body. • The glands and muscles • Divided into two categories…the sympathetic and the parasympathetic

31. Autonomic Nervous System (ANS) • Sympathetic Nervous System: • Fight or Flight Response during stressful situations. • Automatically accelerates heart rate, breathing, dilates pupils, slows down digestion. Parasympathetic Nervous System: • calms the body, conserving its energy. • Provides homeostasishomeo = same Homeostasis means same state you were in before you saw the dog!

32. Think how the right side is different from the left side. Lie detector http://videos.howstuffworks.com/discovery/6833-human-body-how-polygraph-tests-work-video.htm

33. A Simple Reflex

35. Mouse lab • http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html