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National Child Development Study (NCDS): A Longitudinal Study of the 1958 British Birth Cohort

The NCDS is a longitudinal birth cohort study that has followed the lives of all babies born in a single week in Great Britain in 1958. With high retention rates and multidisciplinary content, the study provides insights into social and biomedical factors that influence child development. The study has collected data through repeated follow-ups from birth to age 62, including examination entry details, performance data, and biomedical data. The study aims to examine the long-term effects of early-life circumstances, intergenerational transmission of advantage and disadvantage, and the drivers and consequences of life trajectories.

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National Child Development Study (NCDS): A Longitudinal Study of the 1958 British Birth Cohort

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  1. An Introduction to the National Child Development Study (NCDS, or the 1958 British birth cohort study) David Bann

  2. Longitudinal birth cohort study of all babies born in a single week in GB, N=17,415 • Repeated follow-ups from birth to 62y • High retention, >9k in recent sweeps • (study in touch with 12.5k) • Multidisciplinary content spanning social and biomedical • PI: Alissa Goodman • Co-Is: David Bann, Gabriella Conti • Lead study manager: Matt Brown Brief overview of NCDS

  3. NCDS study timeline Mother and Child Survey – a sample of 1 in 3 cohort member (cog, beh) 1978 - collection of examination entry and performance details 2002/3 biomedical data collection First web data collection (mixed mode) Consent for record linkages Cohort profile

  4. NCDS 58 A study of everyone born in one week in 1958 main respondent secondary respondent In 1965, 1969 and 1974 the cohort was augmented by the addition of immigrants to Britain who were born in the target week in 1958 survey instruments linked data response rate

  5. Topics covered by life stage

  6. Childhood cognition age See also childhood ‘non-cog’ (socioemotional skills) childhood psychological factors etc

  7. Age 44/5 biomedical sweep Approximately 9,000 study members took part at age 44/5 (2002/3) • Biosamples: blood, saliva • Blood pressure, pulse • Standing and sitting height • Weight, waist and hip circumferences • Respiratory symptoms, ventilatory function (FEV1 and FVC) • Visual acuity (near and distant), refractive error • Hearing thresholds • Depression and anxiety disorder (CIS-R) • Chronic widespread pain • Use of medications • Alcohol use (AUDIT) • Food frequency questionnaire, exercise Early & late morning saliva cortisol Glycosylated haemoglobin fibrinogen Tissue plasminogen activator Von Willebrand factor C-reactive protein Triglycerides Total and HDL cholesterol Total and allergen-specific immunoglobulin E Insulin-like growth factor 1 Vitamin D DNA Lymphoblastoid cell lines Genetic data Epigenetic data (N=240+300 underway)

  8. Access to genetic data and biological samples via META-DAC Genetic data: use in phenotype/genotype linkage (eg, GWAS, Mendelian randomisation). Biological samples: apply to further assay whole blood, serum, saliva at 44/45y metadac.ac.uk/1958bc-resource-types/

  9. Age 55 Survey (2013, web/telephone) - Content • Updating event histories (household composition, children, housing, economic activity, qualifications) • Help and care provided to parents and grandchildren • Earnings/income/ housing wealth • Retirement plans / pensions • Voting • Self-reported health and health conditions – disability (Equality Act 2010) • Smoking and drinking

  10. Some recent findings

  11. Age 62 Survey Content • Questionnaire: • Family, relationships and identity: • Social networks, relationships with partners, parents, children, friends, neighbourhood, social capital, social and political participation, attitudes and values, religion, expectations. • Finances and employment: • Work, income, wealth (savings and debts, pensions, and housing), retirement plans, inheritance (receiving and giving) and other transfers, financial literacy, education • Health, well-being and cognition: • Physical & mental health, mental wellbeing, loneliness, medical care, medication, smoking, drinking, diet, exercise, sleep, cognitive function (as per NCDS Age 50 and BCS70 Age 46) • Nurse measures: • Anthropometry, physical function (grip, balance, walking speed), blood pressure (sitting/standing), blood sample (centrifuged at home) • Online diet questionnaire (Oxford WebQ: 2x24 hour recall – as per BCS70) • Life-history paper questionnaire • Validate retrospective data collected by other longitudinal studies which started in later life (e.g. ELSA, SHARE, HRS); Fill in ‘gaps’ • Main stage of data collection – January 2020 to June 2021 • Data available – Early 2022 cls link

  12. Scientific questions and contribution of NCDS • Long term effects of early life circumstances • Intergenerational transmission of advantage and disadvantage and the processes involved • Returns to choices and investments made across life • Drivers & consequences of life trajectories – health, SES, family • Cross-cohort comparative research eg, social mobility, health inequality

  13. Thanks to our funders and host institution Funded by www.esrc.ac.uk Hosted by www.ioe.ac.uk

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