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Evolution of Evolvability Complexity Club Alan N. Hampton 25th August, 2003

Evolution of Evolvability Complexity Club Alan N. Hampton 25th August, 2003. Talk Organization. Interacting elements and complexity Structured evolution of protein networks Does this happen in biology? The evolution of programming languages. Interacting elements and complexity.

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Evolution of Evolvability Complexity Club Alan N. Hampton 25th August, 2003

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  1. Evolution of EvolvabilityComplexity ClubAlan N. Hampton25th August, 2003

  2. Talk Organization • Interacting elements and complexity • Structured evolution of protein networks • Does this happen in biology? • The evolution of programming languages

  3. Interacting elements and complexity

  4. Interacting elements and complexity

  5. Interacting elements and complexity

  6. The evolution of protein networks protein interaction matrix

  7. The evolution of protein networks • Ingredients for evolution • Self reproductory system • Point mutations (square in interaction matrix) • Survival of fittest This has led to living beings as we know it?

  8. The evolution of protein networks • Modular design • Proteins are loosely coupled • Useful sub-functions increase coupling • 3. Loose coupling between sub-functions

  9. The evolution of protein networks

  10. The evolution of protein networks • Faster evolution • Structured mutation • Sub-function duplication Evolution of mutation operator.

  11. Does this happen in biology? • Modules in biological systems (Nature 1999) • Self-regulation of point mutations (e.coli) • Hox genes (module development on/off) • Specificity in chromosome crossover No evidence of structural mutations.

  12. The evolution of programming languages • Machine Code • Assembler • Interpreters (Basic) • Compiler languages (Fortran, Lisp, C) • Object Oriented (C++) Has evolved for the convenience of the developer

  13. The evolution of programming languages Artificial evolution of programming languages? Not very successful (serial language) Any solution? Evolve mutation templates? for (x=0; x < …; x++) { … } int …(…) { … return (int)…; }

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