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The informed patient meeting the laboratory director on metrology and measurands. Explore the basics and the International Vocabulary of Metrology (VIM). Learn about important laboratory tests like serum creatinine and thyroid stimulating hormone (TSH).
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All you wanted to know about laboratory tests, but were afraid to ask The informed patient meeting the laboratory director Metrology Measurand 1 By Dietmar Stöckl STT Consulting - 2 -
Metrology Without your husband? It will be boaring he said! We should understand the basics, I said! Otherwise, we may be lost from the start. You have a point there. All you wanted to know about laboratory tests -2-
VIM – The metrologist’s bible It’s all about measurement International vocabulary of metrology (VIM) Measurand Quantity intended to be measured I knew it was thunderstorms! Quantity format: “System–Component (analyte); Kind of quantity” Serum–creatinine; amount-of-substance concentration, x µmol/L All you wanted to know about laboratory tests -2-
Measurand S-creatinine Alkaline picrate active substances! (Jaffe) Creatinine! (Enzymatic) I knew it was thunderstorms! All you wanted to know about laboratory tests -2-
Measurand It's CREATININE! Quantity intended to be measured NO! All clinical studies were with Jaffe! It's CREATININE! eGFR: trueness-based just introduced All you wanted to know about laboratory tests -2-
Measurand It's CREATININE, I type I knew why I did'nt want to come! All you wanted to know about laboratory tests -2-
The next visit More about measurands Thyroid stimulating hormone (TSH) All you wanted to know about laboratory tests -2-
Resources • ISO/IEC Guide 99:2007. International vocabulary of metrology – Basic and general concepts and associated terms (VIM). International Organization for Standardization: Geneva, 2007 (VIM = Vocabulaire International de Métrologie). • JCGM 200:2008. International vocabulary of metrology – Basic and general concepts and associated terms (VIM). International Bureau of Weights and Measures (BIPM); Joint Committee for Guides in Metrology (JCGM): Paris, 2008. • Freely available at: • http://www.bipm.org/en/publications/guides/vim.html • See also, Clinical and Laboratory Standards Institute (CLSI): http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized_Terminolo.htm All you wanted to know about laboratory tests -2-