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The Liver. Glc. Glc. Glc Glc6P glycogen G1P G6P Glc. Glycerol Lactate Alanine. Glycerol Lactate Alanine. Glycolysis Krebs. OUT. Fatty Acids (Diet). Fatty Acids. VLDL (chol, TAG). VLDL (chol, TAG). IN. Fatty Acids (adipose). Fatty Acids (adipose). ketone bodies.
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The Liver Glc Glc Glc Glc6P glycogen G1P G6P Glc Glycerol Lactate Alanine Glycerol Lactate Alanine Glycolysis Krebs OUT Fatty Acids (Diet) Fatty Acids VLDL (chol, TAG) VLDL (chol, TAG) IN Fatty Acids (adipose) Fatty Acids (adipose) ketone bodies ketone bodies AcetylCoA Glucogenic Ala,Ser, Cys Gly, Thr, Trp Other glucogenic AA Pyruvate Amino Acids Amino Acids Arg, Gln, Glu, Pro, His to aKG Ile, Met, Val to succCoA Asp, Phe, Tyr to fumarate Asp, Arg to OAA Ketogenic Ile, Leu, Thr, Trp (Leu, Lys, Phe, TyrAcAc AcetyCoA AA1 + aKG OAA + Glu